產(chǎn)品編號 | bs-20064R |
英文名稱 | Rabbit Anti-GRTP1 antibody |
中文名稱 | 生長激素調(diào)節(jié)TBC蛋白1抗體 |
別 名 | FLJ22474; Growth hormone-regulated TBC protein 1; Grtp1; GRTP1_HUMAN; MGC138328; MGC138330; OTTHUMP00000018752; TBC1 domain family member 6; TBC1 domain family, member 6; TBC1D6. |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 生長因子和激素 G蛋白偶聯(lián)受體 G蛋白信號 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 39kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GRTP1: 231-336/336 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
GRTP1 is a 336 amino acid protein with expression modulated by growth hormone. The TBC1 domain of GRTP1 is a region that is notably conserved among GTPase-activating proteins, which characteristically play a role in the cell cycle and mitosis coordination. Interestingly, expression of GRTP1 is significantly upregulated in post-puberty testis and then maintained in the adult, suggesting that the germ cell may be the major site of GRTP1 function. There are two isoforms of GRTP1, which are a result of alternative splicing events. Function: May act as a GTPase-activating protein for Rab family protein(s). Similarity: Contains 1 Rab-GAP TBC domain. SWISS: Q5TC63 Gene ID: 79774 Database links: Entrez Gene: 79774 Human Entrez Gene: 66790 Mouse SwissProt: Q5TC63 Human SwissProt: Q9D3N8 Mouse Unigene: 170904 Human Unigene: 34901 Mouse Unigene: 19589 Rat |