| 產(chǎn)品編號 | bs-19892R |
| 英文名稱 | Rabbit Anti-PARVA antibody |
| 中文名稱 | 基質(zhì)重塑相關(guān)蛋白PARVA抗體 |
| 別 名 | Actopaxin; Alpha parvin; Alpha-parvin; Calponin like integrin linked kinase binding protein; Calponin-like integrin-linked kinase-binding protein; CH ILKBP; CH-ILKBP; FLJ10793; FLJ12254; Matrix remodelling associated 2; Matrix remodelling associated protein 2; Matrix-remodeling-associated protein 2; MXRA 2; MXRA2; PARV A; PARVA; PARVA_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 42kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PARVA: 21-120/372 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010] Function: Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Plays a role in ciliogenesis. Subcellular Location: Cell junction > focal adhesion. Cell membrane. Cytoplasm > cytoskeleton. Constituent of focal adhesions. Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. Similarity: Belongs to the parvin family. Contains 2 CH (calponin-homology) domains. SWISS: Q9NVD7 Gene ID: 55742 Database links: Entrez Gene: 55742 Human Entrez Gene: 57342 Mouse Omim: 608120 Human SwissProt: Q9NVD7 Human SwissProt: Q9EPC1 Mouse Unigene: 432914 Human Unigene: 143763 Mouse Unigene: 92564 Rat |
