產(chǎn)品編號 | bs-19911R |
英文名稱 | Rabbit Anti-PCDH19 antibody |
中文名稱 | 原鈣粘附蛋白19抗體 |
別 名 | KIAA1313; PCD19_HUMAN; PCDH19; Protocadherin 19; Protocadherin-19. |
研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞粘附分子 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 124kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PCDH19: 151-250/1148 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010] Function: Potential calcium-dependent cell-adhesion protein. Subcellular Location: Cell membrane. Tissue Specificity: Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast. DISEASE: Epileptic encephalopathy, early infantile, 9 Similarity: Contains 6 cadherin domains. SWISS: Q8TAB3 Gene ID: 57526 Database links: Entrez Gene: 57526 Human Entrez Gene: 101125719 Gorilla Entrez Gene: 100059478 Horse Entrez Gene: 279653 Mouse Omim: 300460 Human SwissProt: Q8TAB3 Human SwissProt: Q80TF3 Mouse Unigene: 4993 Human Unigene: 39738 Mouse |
產(chǎn)品圖片 | |