產(chǎn)品編號 | bs-21015R |
英文名稱 | Rabbit Anti-Pannexin 1 antibody |
中文名稱 | 間隙連接蛋白PANX1抗體 |
別 名 | innexin; MRS1; Pannexin 1; Pannexin-1; Panx1; PANX1_HUMAN; PX1; UNQ2529. |
研究領域 | 細胞生物 神經(jīng)生物學 細胞粘附分子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應 | Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Horse) |
產(chǎn)品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 48kDa |
細胞定位 | 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Pannexin 1: 61-106/426 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008] Function: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Subunit: Homohexamer. Forms homomeric or PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes (By similarity). Subcellular Location: Cell membrane. Cell junction > gap junction. Endoplasmic reticulum membrane. Similarity: Belongs to the pannexin family. SWISS: Q96RD7 Gene ID: 24145 Database links: Entrez Gene: 24145 Human Entrez Gene: 55991 Mouse Entrez Gene: 100171730 Orangutan Omim: 608420 Human SwissProt: Q96RD7 Human SwissProt: Q9JIP4 Mouse SwissProt: Q5REE3 Orangutan Unigene: 591976 Human Unigene: 142253 Mouse Unigene: 204521 Rat |
產(chǎn)品圖片 | |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關于肽鏈的設計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |