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Rabbit Anti-SLC36A2  antibody (bs-21271R)  
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產(chǎn)品編號 bs-21271R
英文名稱 Rabbit Anti-SLC36A2  antibody
中文名稱 溶質(zhì)載體轉(zhuǎn)運(yùn)蛋白家族36成員A2抗體
別    名 A530067G19Rik; FLJ16051; MGC119658; MGC119660; PAT2; Proton coupled amino acid transporter 2; Proton/amino acid transporter 2; Solute carrier family 36 (proton/amino acid symporter) member 2; Solute carrier family 36 member 2; TRAMD1; Tramdorin 1; Tramdorin.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC36A2: 261-360/483 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010]

Function:
SLC36A2 belongs to the amino acid/polyamine transporter 2 family and is involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids such as glycine, alanine and proline. It is inhibited by sarcosine.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cytoplasm.

Tissue Specificity:
Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus.

Similarity:
Belongs to the amino acid/polyamine transporter 2 family.

SWISS:
Q495M3

Gene ID:
153201

Database links:

Entrez Gene: 153201 Human

Omim: 608331 Human

SwissProt: Q495M3 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC36A2) Polyclonal Antibody, Unconjugated (bs-21271R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC36A2) Polyclonal Antibody, Unconjugated (bs-21271R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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