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Rabbit Anti-SLC22A11  antibody (bs-20723R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-20723R
英文名稱 Rabbit Anti-SLC22A11  antibody
中文名稱 有機陰離子轉運體4抗體
別    名 hOAT4; MGC34282; OAT4; Organic anion transporter 4; Solute carrier family 22 (organic anion/urate transporter) member 11; Solute carrier family 22 member 11; S22AB_HUMAN.   
研究領域 腫瘤  信號轉導  生長因子和激素  通道蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC22A11: 21-120/550 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Function:
Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.

Subcellular Location:
Cell membrane, Multi-pass membrane protein.

Tissue Specificity:
Detected in placenta and kidney.

Post-translational modifications:
N-glycosylated. Contains several complex-type N-glycans.

Similarity:
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

SWISS:
Q9NSA0

Gene ID:
55867

Database links:

Entrez Gene: 55867 Human

Omim: 607097 Human

SwissProt: Q9NSA0 Human



產品圖片
Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SLC22A11) Polyclonal Antibody, Unconjugated (bs-20723R) at 1:400 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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