產(chǎn)品編號(hào) | bs-20535R |
英文名稱 | Rabbit Anti-ZNF143 antibody |
中文名稱 | 鋅指蛋白143抗體 |
別 名 | MGC66276; mStaf; pHZ 1; SBF; Selenocysteine tRNA gene transcription activating factor; SPH binding factor; STAF; Zfp143; zgc:66276; Zinc finger protein 143. |
研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 69kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF143: 51-150/638 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
ZNF143 is a human homolog of Xenopus transcriptional activator staf that is involved in selenocystyl tRNA transcription which binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Function: Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8. Subunit: Interacts with CHD8. Subcellular Location: Nuclear. Tissue Specificity: Expressed in all tissues tested, with the strongest expression in ovary. Similarity: Belongs to the GLI C2H2-type zinc-finger protein family. Contains 7 C2H2-type zinc fingers. SWISS: P52747 Gene ID: 7702 Database links: Entrez Gene: 7702 Human Omim: 603433 Human SwissProt: P52747 Human SwissProt: O70230 Mouse Unigene: 523471 Human |