吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
1000部精品久久久久久久久,亚洲中文字幕无码AV,精品国产一区二区三区久久
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Rabbit Anti-Nanog  antibody (bs-23500R)  
~~~促銷(xiāo)代碼KT202411~~~
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō)明書(shū): 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢(xún)價(jià)

產(chǎn)品編號(hào) bs-23500R
英文名稱(chēng) Rabbit Anti-Nanog  antibody
中文名稱(chēng) 胚胎干細(xì)胞關(guān)鍵蛋白抗體
別    名 NANOG_HUMAN; Embryonic stem cell specific homeobox protein (Nanog); ENK; FLJ12581; FLJ40451; Homeobox transcription factor Nanog; Nanog homeobox; Homeobox protein NANOG; ES cell-associated protein 4; Early embryo specific expression NK-type homeobox protein; Homeobox transcription factor Nanog; Nanog; Ecat4.  
研究領(lǐng)域 腫瘤  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞周期蛋白  細(xì)胞表面分子  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nanog: 111-210/305 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Nanog is a newly identified homeodomain-bearing transcriptional factor. Nanog expression is specific to early embryos and pluripotential stem cells including mouse and human embryonic stem (ES) and embryonic germ (EG) cells. It is a key molecule involved in the signaling pathway for maintaining the capacity for self-renewal and pluripotency, bypassing regulation by the STAT3 pathway. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Nanog-deficient ES cells lose pluripotency and differentiate into extraembryonic endoderm lineage. Thus it is one of the molecular markers suitable for recognizing the undifferentiated state of stem cells in the mouse and human.
NANOG is a new marker for testicular carcinoma in situ and germ cell tumors.
NANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency. In other words, these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm).

Function:
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. When overexpressed, promotes cells to enter into S phase and proliferation.

Subunit:
Interacts with SMAD1 and SALL4.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and oocytes.

Similarity:
Belongs to the Nanog homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q9H9S0

Gene ID:
79923

Database links:

Entrez Gene: 100293888 Human

Entrez Gene: 79923 Human

Entrez Gene: 71950 Mouse

Omim: 607937 Human

SwissProt: Q9H9S0 Human

Unigene: 635882 Human



研究表明;早期胚胎在沒(méi)有Nanog存在的情況下是不能存活的,但是這一蛋白的表達(dá)水平至今還有待于進(jìn)一步研究。學(xué)者認(rèn)為:Nanog依然是一種對(duì)于生殖細(xì)胞(germ lls)形成的必要因子,Nanog也是調(diào)控著細(xì)胞融合后的多重功能的關(guān)鍵因子。
胚胎干細(xì)胞是當(dāng)今生命科學(xué)和生物技術(shù)研究的熱點(diǎn),這主要是由于其具有“發(fā)育全能性”的功能。ES能分化成人體200多種細(xì)胞類(lèi)型,形成機(jī)體的任何細(xì)胞、組織和器官。通過(guò)掌握其分化發(fā)育的規(guī)律,在人工條件下定向分化為所需的細(xì)胞、組織乃至器官,科學(xué)家們希望可以用來(lái)治療目前還難以或無(wú)法治愈的帕金森氏病、早老性癡呆、白血病、糖尿病等頑癥,并且解決十分緊缺的組織和器官移植的來(lái)源問(wèn)題,并且通過(guò)進(jìn)一步與克隆技術(shù)相結(jié)合,運(yùn)用體細(xì)胞核轉(zhuǎn)移技術(shù)來(lái)得到ES,還能解決細(xì)胞治療以及組織和器官移植的免疫排異難題。
產(chǎn)品圖片
Sample: DU145(Human) Cell Lysate at 30 ug Primary: Anti-Nanog (bs-23500R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 34 kD
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产农村妇女毛片精品久久| 青柠在线影院观看日本| 国产亚洲成AV人片在线观黄桃| 隔着内裤揉搓她的花蒂H漫画| 免费A级毛片无码| 上司人妻互换中文字幕| 特级毛片爽WWW免费版| 人人妻人人澡人人爽精品日本| 老妇性hqmaturetube| 亚洲av高清一区二区三区| 亚洲中文字幕无码AV永久| 久久人妻少妇嫩草AV无码专区| 波多野结衣网站| 久久99精品国产麻豆不卡| 日本丰满熟妇BBXBBXHD| 欧洲站特大码胖MM潮流女装| 无码AV中文字幕久久专区| 精品国产AV一区二区三区| 熟睡人妻被讨厌的公侵犯| 亚洲尺码与欧洲尺码区别入口跳转| 99久久精品免费看国产一区二区三区| 闺蜜男友猛撞H花液H深| 国产在线拍偷自揄拍无码成人小说| 熟妇人妻VA精品中文字幕| 按摩高潮A片一区二区三区| 一本一道AV无码中文字幕| 国内精品一区二区三区| 丰满的人妻hd高清日本| B站禁止转播404入口| 女人被强╳到高潮喷水在线观看| 国产精品第一页| 国产成人精品无码一区二区| 日本动漫瀑乳H动漫啪啪免费| 性色AV蜜臀AV色欲AV| 国产片XXXXA片国语对白| 国产AV无码专区亚洲AV麻豆 | A片粗大的内捧猛烈进出男男小说 无码人妻丰满熟妇啪啪网站 | 少妇AAA级久久久无码精品片| 18videosex性欧美69| 和寡妇房东在做爰HD| 兽性新人类1|