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Rabbit Anti-CD2  antibody (bs-23946R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-23946R
英文名稱 Rabbit Anti-CD2  antibody
中文名稱 CD2抗體
別    名 CD2_HUMAN; T-cell surface antigen CD2; T cell surface antigen CD2; SRBC; Erythrocyte receptor; LFA-2; LFA2; LFA3 receptor; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD 2; CD2 antigen; CD2 molecule;  
研究領(lǐng)域 細胞生物  免疫學  干細胞  細胞表面分子  糖蛋白  自然殺傷細胞  淋巴細胞  t-淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Rat,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse CD2: 101-200/344 <Extracellular>
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. A locus control region (LCR) has been found in the 3' flanking sequence of this gene. [provided by RefSeq, Jun 2016]

Function:
CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Subunit:
Interacts with CD2AP. Interacts with PSTPIP1.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P08920

Gene ID:
12481

Database links:

Entrez Gene: 914 Human

Entrez Gene: 12481 Mouse

Entrez Gene: 497761 Rat

Omim: 186990 Human

SwissProt: P06729 Human

SwissProt: P08920 Mouse

SwissProt: P08921 Rat

Unigene: 523500 Human

Unigene: 22842 Mouse

Unigene: 10328 Rat



產(chǎn)品圖片
Sample: Lane 1: Mouse Lymph node tissue lysates Lane 2: Rat Thymus tissue lysates Primary: Anti-CD2 (bs-23946R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 37 kDa Observed band size: 60 kDa
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