| 產(chǎn)品編號(hào) | bs-22862R |
| 英文名稱 | Rabbit Anti-IGFBP3 antibody |
| 中文名稱 | 胰島素樣生長(zhǎng)因子結(jié)合蛋白3抗體 |
| 別 名 | IBP3_HUMAN; Insulin-like growth factor-binding protein 3; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IBP3; BP-53; |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 生長(zhǎng)因子和激素 糖尿病 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse,Rat (predicted: Human,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 32kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IGFBP3: 131-231/292 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Subcellular Location: Secreted. Tissue Specificity: Expressed by most tissues. Present in plasma. Post-translational modifications: Phosphorylation sites are present in the extracelllular medium. Similarity: Contains 1 IGFBP N-terminal domain. Contains 1 thyroglobulin type-1 domain. SWISS: P17936 Gene ID: 3486 Database links: Entrez Gene: 3486 Human Entrez Gene: 16009 Mouse SwissProt: P17936 Human SwissProt: P47878 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Rat Liver tissue lysates
Primary: Anti-IGFBP3 (bs-22862R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 32 kDa
Observed band size: 46 kDa
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