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Mouse Anti-CD11c  antibody (bsm-51510M)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bsm-51510M
英文名稱 Mouse Anti-CD11c  antibody
中文名稱 整合素αX單克隆抗體
別    名 Integrin alpha-X; Integrin alpha X; integrin alpha-X precursor; ITGAX; SLEB6; CD11C (p150) alpha polypeptide; complement receptor 4; integrin aX; CD11 antigen-like family member C; leukocyte adhesion receptor p150,95; leukocyte adhesion glycoprotein p150,95 alpha chain; ITAX_HUMAN.  
Specific References  (1)     |     bsm-51510M has been referenced in 1 publications.
[IF=7.59] Guoyun Wan. et al. Endoplasmic reticulum-targeted NIR-II phototherapy combined with inflammatory vascular suppression elicits a synergistic effect against TNBC. BIOMATER SCI-UK. 2023 Jan;:  IF ;  Mouse.  
研究領(lǐng)域 細胞生物  免疫學  信號轉(zhuǎn)導  干細胞  細胞粘附分子  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 E6F88
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 126kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD11c: 201-300/1163 
亞    型 IgG1
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq].

Function:
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Subcellular Location:
Membrane.

Tissue Specificity:
Predominantly expressed in monocytes and granulocytes.

Similarity:
Belongs to the integrin alpha chain family. Contains 7 FG-GAP repeats. Contains 1 VWFA domain.

SWISS:
P20702

Gene ID:
3687

Database links:

Entrez Gene: 3687 Human

SwissProt: P20702 Human



產(chǎn)品圖片
Sample: Lane 1: NCI-H292 cell lysates Primary: Anti-CD11c (bsm-51510M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 126 kD Observed band size: 140 kD
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