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Recombinant mouse CD40L protein, His (HEK293) (bs-43030P)  
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產(chǎn)品編號 bs-43030P
英文名稱 Recombinant mouse CD40L protein, His (HEK293)
中文名稱 重組小鼠CD40L蛋白
別    名 TNFSF5; CD 154; CD154; CD 40L; CD154; CD154 antigen; CD40 homologue; CD40 ligand; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T cell antigen GP39; TBAM; TNF related activation protein; TNF superfamily member 5; Tnfsf5; TRAP; Tumor necrosis factor (ligand) superfamily member 5; CD40L_MOUSE; Recombinant mouse CD40L protein, His (HEK293)  
理論分子量 20kDa
性    狀 Lyophilized or Liquid
濃    度 >0.5 mg/ml
物    種 Mouse
序    列 112-260/260
純    度 >95% as determined by SDS-PAGE
純化方法 AC
內(nèi)毒素 Not analyzed
表達系統(tǒng) HEK293 cell
活性 Yes
標簽 His
緩 沖 液 PBS (pH7.4).
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.

SWISS:
P27548

Gene ID:
21947

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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