| 產(chǎn)品編號(hào) | bsm-30307A-PE-Cy7 |
| 英文名稱 | Rat Anti-mouse CD45R/PE-Cy7 antibody |
| 中文名稱 | PE-Cy7標(biāo)記小鼠CD45R單克隆抗體 |
| 抗體來(lái)源 | Rat |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | 3B6 |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Liquid |
| 亞 型 | Rat IgG2a, k |
| 純化方法 | Affinity purified by Protein G |
| 緩 沖 液 | 0.01M PBS, 0.5%BSA, 0.03% Proclin300 |
| 保存條件 | Store at 2-8℃. Protect from light. Avoid freezing. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. SWISS: P06800 Gene ID: 19264 |
