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Rabbit Anti-LPCAT1  antibody (bs-25412R)  
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產(chǎn)品編號(hào) bs-25412R
英文名稱 Rabbit Anti-LPCAT1  antibody
中文名稱 溶血卵磷脂?;D(zhuǎn)移酶1抗體
別    名 PCAT1_HUMAN; Lysophosphatidylcholine acyltransferase 1; AYTL2; PFAAP3; EC:2.3.1.23; LPC acyltransferase 1; LPCAT-1; LysoPC acyltransferase 1; 1-acylglycerol-3-phosphate O-acyltransferase. EC:2.3.1.51; 1-acylglycerophosphocholine O-acyltransferase; 1-alkenylglycerophosphocholine O-acyltransferase. EC:2.3.1.25; 1-alkylglycerophosphocholine O-acetyltransferase. EC:2.3.1.67; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase (Acetyl-CoA:lyso-PAF acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT);   
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 59kDa
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LPCAT1:471-534/534 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Lysophosphatidylcholine (LPC) acyltransferase (LPCAT; EC 2.3.1.23) catalyzes the conversion of LPC to phosphatidylcholine (PC) in the remodeling pathway of PC biosynthesis (Nakanishi et al., 2006 [PubMed 16704971]).[supplied by OMIM, May 2008]

Function:
Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-independent. Mediates the conversion of 1-acyl-sn-glycero-3-phosphocholine (LPC) into phosphatidylcholine (PC). Displays a clear preference for saturated fatty acyl-CoAs, and 1-myristoyl or 1-palmitoyl LPC as acyl donors and acceptors, respectively. May synthesize phosphatidylcholine in pulmonary surfactant, thereby playing a pivotal role in respiratory physiology.

Subcellular Location:
Endoplasmic reticulum membrane. Golgi apparatus membrane.

Similarity:
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

SWISS:
Q8NF37

Gene ID:
79888

Database links:

Entrez Gene: 79888 Human

Entrez Gene: 210992 Mouse

Entrez Gene: 361467 Rat

SwissProt: Q8NF37 Human

SwissProt: Q3TFD2 Mouse

SwissProt: Q1HAQ0 Rat



產(chǎn)品圖片
Sample: Lane 1: Human MCF-7 cell lysates Lane 2: Human HeLa cell lysates Lane 3: Human HepG2 cell lysates Primary: Anti-LPCAT1 (bs-25412R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 59 kDa Observed band size: 59 kDa
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