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Rabbit Anti-PRAME  antibody (bsm-60694R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bsm-60694R
英文名稱 Rabbit Anti-PRAME  antibody
中文名稱 黑色素瘤優(yōu)先表達抗原重組兔單抗
別    名 MAPE; Melanoma antigen preferentially expressed in tumors; OIP 4; OIP-4; OIP4; OPA interacting protein 4; Opa interacting protein OIP4; OPA-interacting protein 4; PRAME_HUMAN; Preferentially expressed antigen in melanoma; Preferentially expressed antigen of melanoma; RP23-250F8.3.  
研究領域 腫瘤  細胞生物  信號轉(zhuǎn)導  腫瘤細胞生物標志物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 R1D8
交叉反應 Human
產(chǎn)品應用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56kDa
細胞定位 細胞核 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PRAME 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]


Subcellular Location:
Nucleus (Probable). Cell membrane.

Tissue Specificity:
Expressed in testis. Detected in samples of kidney, brain and skin.

SWISS:
P78395

Gene ID:
23532

Database links:


Entrez Gene: 23532 Human

SwissProt: P78395 Human




產(chǎn)品圖片
Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:1000 Primary Ab incubation condition: 4℃ overnight Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: Ramos, 2: K562, 3: HeLa, 4: A375 Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 58 kDa Observed MW: 58 kDa
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