產(chǎn)品編號 | V5802 |
英文名稱 | Human UCHL1/PGP9.5 |
中文名稱 | 神經(jīng)細(xì)胞胞漿蛋白9.5/蛋白基因產(chǎn)物9.5單克隆抗體 |
別 名 | Gracile axonal dystrophy; Neuron cytoplasmic protein 9.5; Park 5; Park5; Parkinson Disease 5; PGP 9.5; PGP95; Protein gene product 9.5; Ubiquitin C terminal esterase L1; Ubiquitin C terminal hydrolase (neuron specific); Ubiquitin C terminal hydrolase; Ubiquitin carboxyl terminal esterase L1; Ubiquitin carboxyl terminal hydrolase isozyme L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin thioesterase L1; Ubiquitin thiolesterase; Ubiquitin thiolesterase L1; UCH-L1; UCHL1_HUMAN. |
理論分子量 | 25kDa |
緩 沖 液 | 0.01M PBS(pH7.4). |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
catalyzes the hydrolysis of ubiquitin carboxy-terminal thiolesters to form ubiquitin and a thiol; may play a role in neuropathic pain [RGD].
Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients. 該抗原是一種神經(jīng)特異性蛋白,廣泛分布于中樞與外周神經(jīng)系統(tǒng)的神經(jīng)元和神經(jīng)纖維、神經(jīng)內(nèi)分泌細(xì)胞、腎小管段、睪丸精原細(xì)胞、Leydig細(xì)胞、卵細(xì)胞以及妊娠與非妊娠黃體內(nèi)的某些細(xì)胞。用于標(biāo)記神經(jīng)元,對研究幾種人慢性神經(jīng)變性性疾病中廣泛存在的細(xì)胞包涵體特征較有意義。 |