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Rabbit Anti-FUT8  antibody (bs-24389R)  
~~~促銷代碼KT202411~~~
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產(chǎn)品編號 bs-24389R
英文名稱 Rabbit Anti-FUT8  antibody
中文名稱 巖藻糖轉(zhuǎn)移酶8抗體
別    名 Alpha (1,6) fucosyltransferase; Alpha-(1; Alpha1 6FucT; alpha1-6FucT; Fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Fucosyltransferase 8; FUT8; FUT8_HUMAN; GDP fucose glycoprotein fucosyltransferase; GDP L Fuc:N acetyl beta D glucosaminide alpha1,6 fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1; Glycoprotein 6 alpha L fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; 6)-fucosyltransferase; 6-fucosyltransferase.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  腫瘤細(xì)胞生物標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,Rat (predicted: Human,Rabbit,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 66kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FUT8 : 201-300/575 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. There are 2 isoforms produced by alternative splicing. Immunogen is not present in isoform 2 (also known as Retinal).

Function:
Catalyzes the addition of fucose in alpha 1-6 linkage tocthe first GlcNAc residue, next to the peptide chains in N-glycans.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the glycosyltransferase 23 family.
Contains 1 SH3 domain.

SWISS:
Q9BYC5

Gene ID:
2530

Database links:
Entrez Gene: 2530 Human

Entrez Gene: 53618 Mouse

Entrez Gene: 432392 Rat

Omim: 602589 Human

SwissProt: Q9BYC5 Human

SwissProt: Q9WTS2 Mouse

SwissProt: Q6EV76 Rat

Unigene: 654961 Human

Unigene: 35628 Mouse

Unigene: 1717 Rat


產(chǎn)品圖片
Sample: Lane 1: Lung (Mouse) Lysate at 40 ug Lane 2: Lung (Rat) Lysate at 40 ug Primary: Anti-FUT8 (bs-24389R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 66 kD Observed band size: 70 kD
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