| 產(chǎn)品編號(hào) | D50681 |
| 英文名稱 | Dactolisib Tosylate |
| 中文名稱 | NVP-BEZ235 對(duì)甲苯磺酸鹽 |
| 別 名 | BEZ235 Tosylate; NVP-BEZ 235 Tosylate; BEZ235 (Tosylate); BEZ235 對(duì)甲苯磺酸鹽; PI3K和MTOR雙重激酶抑制劑; PI3K抑制劑; mTOR抑制劑; |
| 保存條件 | Store at -20℃ for 3 year(Powder); In DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
CAS：1028385-32-1 分子式：C37H31N5O4S 分子量：641.7382 MDL：MFCD22124509 純度：≥99.8% (HPLC) 溶解性：溶于DMSO, 作用靶點(diǎn)：PI3K; mTOR; Autophagy; 作用通路：PI3K/Akt/mTOR; Autophagy; 產(chǎn)品描述：Dactolisib Tosylate (BEZ235 Tosylate) 是PI3K和mTOR的雙重激酶抑制劑，對(duì)PI3Kα, β, γ, δ 的IC50值分別為4, 75, 7, 5 nM。Dactolisib Tosylate (BEZ235 Tosylate) 抑制 mTORC1 和 mTORC2。 |
