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Rabbit Anti-CACNB1/Gold Conjugated antibody (bs-6517R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
技術支持:techsupport@xucheq.com
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6517R-Gold
英文名稱1 Rabbit Anti-CACNB1/Gold Conjugated antibody
中文名稱 膠體金標記的鈣通道電壓依賴性β1蛋白抗體
別    名 CAB1; CACNLB1; Calcium channel voltage dependent beta 1 subunit; Voltage dependent L type calcium channel beta 1 subunit; CACB1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  信號轉導  轉錄調(diào)節(jié)因子  通道蛋白  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 66kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CACNB1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by CACNB1 belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation.

Function:
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

Subunit:
The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. Interacts with JSRP1. Interacts with RYR1 (By similarity).

Subcellular Location:
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.

Tissue Specificity:
Isoform 1 and isoform 3 are expressed in brain, heart, spleen, central nervous system and neuroblastoma cells. Isoform 2 is expressed in skeletal muscle.

Similarity:
Belongs to the calcium channel beta subunit family.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 327703 Cow

Entrez Gene: 782 Human

Entrez Gene: 12295 Mouse

Entrez Gene: 50688 Rat

Omim: 114207 Human

SwissProt: Q9MZL7 Cow

SwissProt: Q02641 Human

SwissProt: Q8R3Z5 Mouse

SwissProt: P19517 Rabbit

SwissProt: P54283 Rat

Unigene: 635 Human

Unigene: 41252 Mouse

Unigene: 9417 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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