吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
狠狠色综合7777久夜色撩人,,熟妇人妻AV无码一区二区三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Exportin 1/Biotin Conjugated antibody (bs-2953R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2953R-Bio
英文名稱1 Rabbit Anti-Exportin 1/Biotin Conjugated antibody
中文名稱 生物素標記的染色體區(qū)域穩(wěn)定蛋白/核輸出蛋白1/染色體區(qū)域穩(wěn)定必需蛋白抗體
別    名 Chromosome region maintenance 1 protein homolog; CRM 1; CRM1; CRM1 homolog; DKFZp686B1823; Exp 1; Exp-1;Exp1; Exportin 1; Exportin1; Exportin-1; XPO 1; XPO1; XPO1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, )
產(chǎn)品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 118kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Exportin 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CRM1 (chromosome region maintenance 1 protein homolog) mediates the nuclear export of cellular proteins (cargoes) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, CRM1 binds cooperatively to the NES on its target protein and to the GTPase Ran in its active GTP-bound form. Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. The direction of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. CRM1 also mediates the nuclear export of the Rev protein of HIV-1 and Rex protein of HTLV-1. It is involved in Rex dimerization, U3 snoRNA transport from Cajal bodies to nucleoli.
CRM1 is also involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. CRM1 is also involved in the regulation NFAT and AP-1.


Subunit:
Found in a U snRNA export complex with RNUXA/PHAX, NCBP1, NCBP2, RAN, XPO1 and m7G-capped RNA (By similarity). Component of a nuclear export receptor complex composed of KPNB1, RAN, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, RAN and XPO1. Found in a nuclear export complex with RANBP3 and RAN. Found in a 60S ribosomal subunit export complex with NMD3, RAN, XPO1. Interacts with DDX3X, NMD3, NUPL2, NUP88, NUP214, RANBP3 and TERT. Also found in complex with several viral proteins involved in RNAs' nuclear export like HIV-1 Rev and HTLV-1 Rex. Interacts presumably with influenza A nucleoprotein. Interacts with Epstein-Barr virus BMLF1. Interacts with NEMF (via its N-terminus). Interacts with the monomeric form of BIRC5/survivin deacetylated at 'Lys-129'.

Subcellular Location:
Cytoplasm. Nucleus, nucleoplasm. Nucleus, Cajal body. Nucleus, nucleolus. Note=Located in the nucleoplasm, Cajal bodies and nucleoli. Shuttles between the nucleus/nucleolus and the cytoplasm.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes. Not expressed in the kidney.

Similarity:
Belongs to the exportin family.
Contains 10 HEAT repeats.
Contains 1 importin N-terminal domain.

Database links:

Entrez Gene: 7514 Human

Entrez Gene: 103573 Mouse

Entrez Gene: 85252 Rat

Omim: 602559 Human

SwissProt: O14980 Human

SwissProt: Q6P5F9 Mouse

SwissProt: Q80U96 Rat

Unigene: 370770 Human

Unigene: 217547 Mouse

Unigene: 34087 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久久久久久亚洲AV无码 | 重囗味SM在线观看无码| 亚洲AV成人无码久久精品老人 | 99久久久精品免费观看国产| 国产草草影院CCYYCOM| 欧美JIZZ18性欧美| 亚洲AV无一区二区三区久久| 日本人妻伦在线中文字幕| 亚洲小说区图片区另类春色| 99久久久无码国产精品9| 强行无套内谢大学生初次| 成人视频在线观看| 亚洲精品无码久久久影院相关影片| 业余 自由 性别 成熟偷窥| 亚洲AV中文无码乱人伦在线观看| 国产真人免费无码AV在线观看| 性少妇FREESEXVIDEOS高清| 久久久久亚洲精品中文字幕| 亚洲欧美国产精品专区久久 | 国内少妇偷人精品视频免费| 精品国产一区二区三区AV性色| 日韩人妻无码精品无码中文字幕| 国产亚洲精品久久久无码| 少妇AV一区二区三区无码| 大乳丰满人妻中文字幕日本| 18VIDEOSEX性欧美69| 女性女同性AⅤ免费观女性恋| 日韩欧美高清DVD碟片| 欧美老熟妇XB水多毛多| 亚洲AV无码专区国产乱码不卡| 蜜桃成人无码区免费视频网站 | 精品人妻系列无码人妻免费视频| 国产亚洲精品AAAA片小说| 亚洲精品国产精品国自产观看| 亚洲乱码一区二区三区在线观看| 中文字幕在线观看| 亚洲精品久久久久久一区二区| 国产日韩成人内射视频| 最近2019中文字幕大全第二页| 国产肉体XXXX裸体784大胆| 凹凸国产熟女精品视频APP|