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Rabbit Anti-SART3/Gold Conjugated antibody (bs-7009R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7009R-Gold
英文名稱1 Rabbit Anti-SART3/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的T淋巴細(xì)胞識(shí)別的鱗狀細(xì)胞癌SART3抗體
別    名 p110(nrb); SART3; SART-3; Tat interacting protein of 110 kDa; TIP110; SART3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細(xì)菌及病毒  t-淋巴細(xì)胞  腫瘤細(xì)胞生物標(biāo)志物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 110kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SART3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
RelevanceSART3 regulates Tat transactivation activity through direct interaction. It may be a cellular factor for HIV1 gene expression and viral replication.

Subunit:
Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs. Interacts with HIV-1 Tat. Interacts with EIF2C1 and EIF2C2.

Subcellular Location:
Cytoplasm. Nucleus speckle. Note=Localized in speckles. Expressed in the nucleus of all of the malignant tumor cell lines tested and the majority of cancer tissues with various histologies, including squamous cell carcinomas (SCC), adenocarcinomas, melanomas and leukemias cells. However, this protein is undetectable in the nucleus of any cell lines of nonmalignant cells or normal tissues, except for the testis. Expressed in the cytoplasm of all the proliferating cells, including normal and malignant cells, but not in normal tissues, except for the testis and the fetal liver.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Contains 8 HAT repeats.
Contains 2 RRM (RNA recognition motif) domains.

Database links:
 

UniProtKB/Swiss-Prot: Q15020.1



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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