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Rabbit Anti-AMH/BF350 Conjugated antibody (bs-4687R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4687R-BF350
英文名稱1 Rabbit Anti-AMH/BF350 Conjugated antibody
中文名稱 BF350標記的Muellerian繆勒管激素抑制因子抗體
別    名 MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  發(fā)育生物學  信號轉(zhuǎn)導  干細胞  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 57kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human AMH
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008].

Function:
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

DISEASE:
Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the TGF-beta family.

Database links:

Entrez Gene: 268 Human

Entrez Gene: 11705 Mouse

Entrez Gene: 25378 Rat

Omim: 600957 Human

SwissProt: P03971 Human

SwissProt: P27106 Mouse

SwissProt: P49000 Rat

Unigene: 112432 Human

Unigene: 19121 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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