吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
国产人妻人伦精品,丰满岳乱妇在线观看中字无码
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Kidins220/APC Conjugated antibody (bs-7040R-APC)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7040R-APC
英文名稱1 Rabbit Anti-Kidins220/APC Conjugated antibody
中文名稱 APC標記的220kDa蛋白激酶D相互作用蛋白抗體
別    名 Ankyrin repeat-rich membrane-spanning protein; arms; KDIS_HUMAN; Kidins220; Kinase D interacting substance of 220 kDa; Kinase D-interacting substrate of 220 kDa; rgd 619949.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 心血管  細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導(dǎo)  細胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Cow, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 196kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Kidins220
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway.

Function:
Promotes a prolonged MAP-kinase signaling byneurotrophins through activation of a Rap1-dependent mechanism.Provides a docking site for the CRKL-C3G complex, resulting inRap1-dependent sustained ERK activation. May play an important rolein regulating postsynaptic signal transduction through thesyntrophin-mediated localization of receptor tyrosine kinases suchas EPHA4. In cooperation with SNTA1 can enhance EPHA4-inducedJAK/STAT activation. May play a role in neurotrophin- andephrin-mediated neuronal outgrowth and in axon guidance duringneural development and in neuronal regeneration (By similarity).Modulates stress-induced apoptosis of melanoma cells via regulationof the MEK/ERK signaling pathway.

Subunit:
Interacts with NTRK1, NTRK2, NTRK3, ERKL and NGFR. Can form a ternary complex with NGFR and NTRK1 and this complex is affected by the expression levels of KIDINS220/ARMS. An increase in KIDINS220/ARMS expression leads to a decreased association of NGFR and NTRK1. Interacts with SNTA1 and SNTB2 and binds to their PDZ domains. Interacts with EPHA4 and PRKD1.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Tissue Specificity:
Expressed in developing nervous system and in highly plastic areas of the adult brain. Also expressed in neuroendocrine cells, where it concentrates at the tip of neurites. Expressed in developing muscle and is concentrated at the neuromuscular junction (NMS). SNTA1 can regulate its localization in the NMS.

Post-translational modifications:
Tyrosine phosphorylated by NTRK1, NTRK2, EPHB2 and EPHA4.Phosphorylation at Ser-918 is induced by phorbol ester treatment.Phosphorylation by NTRK2 is induced by brain-derived neurotrophicfactor (BDNF) and neurotrophin-4/5. Phosphorylation by NTRK1 isinduced by nerve growth factor (NGF) (By similarity).

Similarity:
Contains 12 ANK repeats.
Contains 1 KAP NTPase domain.

Database links:

Entrez Gene: 57498 Human

Entrez Gene: 77480 Mouse

Entrez Gene: 116478 Rat

SwissProt: Q9ULH0 Human

SwissProt: Q9EQG6 Rat

Unigene: 9873 Human

Unigene: 250641 Mouse

Unigene: 21470 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
人妻丰满熟妇AV无码区乱| 日本高清视频www| 特级毛片WWW| 色欧美片视频在线观看| 欧美巨鞭大战丰满少妇| 肉大捧一进一出免费视频| 天天躁日日躁狠狠躁AV中文| 99蜜桃在线观看免费视频网站| 性高湖久久久久久久久| 久久精品无码一区二区日韩av| 国产97色在线 | 日韩| 亚洲精品无码专区| 国产精品videossex国产高清| 高清欧美性猛交XXXX黑人猛交| 费A级毛片无码免费视频120软件| 女人被强╳到高潮喷水在线观看| 日本理论片| 人妻中文字幕乱人伦在线| 亚洲成熟丰满熟妇高潮XXXXX | 精品久久久久久综合日本| 国产美女精品一区二区三区| 无码人妻少妇色欲AV一区二区| 成年丰满熟妇午夜免费视频| 成熟护士长的蚌肉的滋味| 24小时日本在线WWW免费的| 久久久久亚洲AV无码专区| 亚洲精品乱码久久久久久按摩| 欧美性猛交XXXX| 亚洲熟妇色XXXXX欧美老妇| ZOZ○ZO女人和另类ZOZ0| 国产精品视频一区二区三区不卡| 国内老熟妇对白HDXXXX| 国产人妻久久精品二区三区特黄 | 亚洲中文字幕无码爆乳AV| 少妇粉嫩小泬喷水视频WWW| 国产在线视频一区二区三区| 丰满少妇a级毛片| 99久久精品日本一区二区免费| 欧美激情性做爰免费视频| 国产精品ⅴ无码大片在线看| 人妻夜夜爽天天爽三区丁香花|