| 產(chǎn)品編號(hào) | bs-2411R-BF647 |
| 英文名稱1 | Rabbit Anti-NKG2A/BF647 Conjugated antibody |
| 中文名稱 | BF647標(biāo)記的NK細(xì)胞受體2A抗體 |
| 別 名 | KLRC1; C lectin type II protein; CD159 antigen like family member A; CD159A; Killer cell lectin like receptor subfamily C member 1; MGC13374; MGC59791; Natural killer cell lectin; Natural killer group protein 2; NK cell receptor A; NKG2 1/B activating NK receptor; NKG2 A/B activating NK receptor; NKG2 A/B type II integral membrane protein; NKG2; NKG2A_HUMAN; NKG2-A/NKG2-B type II integral membrane protein; NKG2-A/B-activating NK receptor; NKG2A. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 28kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse NKG2A |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008] Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subunit: Can form disulfide-bonded heterodimer with CD94. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. Database links: Entrez Gene: 3821 Human Entrez Gene: 16641 Mouse Omim: 161555 Human SwissProt: P26715 Human Unigene: 512576 Human Unigene: 56899 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 自然殺傷細(xì)胞活化性受體2A |
