吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
久久人人添人人爽添人人片牛牛 ,日韩精品久久久久久久电影蜜臀
Rabbit Anti-MCM2/APC Conjugated antibody (bs-1981R-APC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-1981R-APC
英文名稱1 Rabbit Anti-MCM2/APC Conjugated antibody
中文名稱 APC標(biāo)記的微小染色體維持缺陷蛋白2抗體
別    名 BM28; CCNL 1; CCNL1; CDC like 1; CDC like-1; cdc19; CDCL 1; CDCL1; Cell devision cycle like 1; Cyclin like 1; cyclin like-1; D3S3194; DNA replication licensing factor MCM2; KIAA0030; MCM 2; MCM2; MCM2 minichromosome maintenance deficient 2 mitotin; MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae); MCM2 minichromosome maintenance deficient 2, mitotin; MCM2_HUMAN; MCM2_MOUSE; MGC10606; Minichromosome maintenance complex component 2; Minichromosome maintenance deficient 2 (mitotin); Minichromosome maintenance deficient 2 mitotin; Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; Mitotin; Nuclear protein BM28; OTTHUMP00000216047; OTTHUMP00000216050.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 染色質(zhì)和核信號(hào)  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Chicken, Dog, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 102kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse MCM2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]

Function:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Subunit:
Component of the MCM2-7 complex. The complex forms a toroidal hexameric ring with the proposed subunit order MCM2-MCM6-MCM4-MCM7-MCM3-MCM5. Interacts with KAT7 and DBF4. May interact with MCM10.

Subcellular Location:
Nucleus (Probable).

Post-translational modifications:
Phosphorylated on Ser-108 by ATR in proliferating cells. Ser-108 proliferation is increased by genotoxic agents. Ser-40 is mediated by the CDC7-DBF4 and CDC7-DBF4B complexes, while Ser-53 phosphorylation is only mediated by the CDC7-DBF4 complex. Phosphorylation by the CDC7-DBF4 complex during G1/S phase is required for the initiation of DNA replication.

Similarity:
Belongs to the MCM family.
Contains 1 MCM domain.

Database links:

Entrez Gene: 4171 Human

Entrez Gene: 17216 Mouse

Entrez Gene: 312538 Rat

Omim: 116945 Human

SwissProt: P49736 Human

SwissProt: P97310 Mouse

Unigene: 477481 Human

Unigene: 16711 Mouse

Unigene: 2715 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

微小染色體維持缺陷蛋白2又稱微型染色體維持蛋白2或絲裂蛋白,MCM-2是細(xì)胞周期階段的特異性標(biāo)志物,在進(jìn)入細(xì)胞周期的細(xì)胞中均有表達(dá),在細(xì)胞的增值、分化中起到一定的作用。
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
丰满少妇a级毛片| 熟妇人妻系列AV无码一区二区| 成年免费A级毛片免费看无码| 精产国品一二三产区区别| 99精品视频在线观看免费| 日本a√在线观看| 女人与公驹交酡全过程| 99久久精品无码一区二区毛片| 国产chinesehdxxxx| 国产欧美日韩A片免费软件| 无套内谢的新婚少妇国语播放 | 强开美妇后菊哀嚎哭叫视频| 日本LAURENPHILIPS| 国产精品一卡二卡三卡| 欧洲亚洲国产精华液| 国产性生交XXXXX免费| 性色av无码| 欧美老熟妇又粗又大| 体验区试看120秒啪啪免费| 麻豆国产尤物AV尤物在线观看| 少妇被粗大的猛烈进出A片久久久 极品少妇被猛得白浆直流草莓视频 | 亚洲午夜精品久久久久久浪潮| 99E久热只有精品8在线直播 | 亚洲欧美一区二区三区在线| 成人区色情综合小说| 少妇AV一区二区三区无码| 实拍各种胸走光见奶头| 亚洲AV无码一区二区三区网址| 国产A级特黄的片子| 亚洲国产精华液网站W| 被老外做的下身都肿了| 国产成人无码AA精品一区| 久久夜色精品国产噜噜亚洲av| 香肠派对比赛服| 亚洲熟妇AV一区二区三区| 国内精品视频一区二区三区八戒| 人妻少妇被猛烈进入中文字幕| 性色AV浪潮AV色欲AV一区| 无码粉嫩虎白一线天在线观看| 老熟妇仑乱视频一区二区| 国产AV麻豆MAG剧集|