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Rabbit Anti-IGFALS/BF647 Conjugated antibody (bs-9904R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-9904R-BF647
英文名稱1 Rabbit Anti-IGFALS/BF647 Conjugated antibody
中文名稱 BF647標記的胰島素樣生長因子酸不穩(wěn)定亞基ALS抗體
別    名 Albs; IGFALS; Insulin like growth factor binding protein acid labile subunit; Insulin like growth factor binding protein complex acid labile chain; MGC150140; MGC150141; KIAA4111; mKIAA4111; ALS_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  信號轉導  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IGFALS
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The Insulin-like growth factor binding proteins, or IGFBPs, are a family of seven proteins that have co-evolved with the IGFs. IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, concentration and distribution of IGFs in the extracellular environment. In human circulation, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), an extracellular protein involved in receptor-ligand binding and cell adhesion. ALS, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein complexes.

Function:
Involved in protein-protein interactions that result inprotein complexes, receptor-ligand binding or cell adhesion.

Subunit:
Forms a ternary complex of about 140 to 150 kDa withIGF-I or IGF-II and IGFBP-3.

Subcellular Location:
Secreted; extracellular space.

Tissue Specificity:
Plasma.

Similarity:
Contains 19 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 3483 Human

Omim: 601489 Human

SwissProt: P35858 Human

Unigene: 839 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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