吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
中文字幕乱妇无码AV在线,无码国产色欲XXXXX视频
Rabbit Anti-KCNJ5/RBITC Conjugated antibody (bs-9931R-RBITC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-9931R-RBITC
英文名稱1 Rabbit Anti-KCNJ5/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標(biāo)記的G蛋白激活內(nèi)向鉀通道5抗體
別    名 inwardly rectifying subfamily J member 5; Cardiac ATP sensitive potassium channel; Cardiac inward rectifier; CIR; G protein activated inward rectifier potassium channel 4; G protein-activated inward rectifier potassium channel 4; GIRK 4; GIRK-4; GIRK4; Heart KATP channel; Inward rectifier K(+) channel Kir3.4; Inward rectifier K+ channel KIR3.4; IRK-4; IRK5_HUMAN; KATP 1; KATP-1; KATP1; KCNJ 5; Kcnj5; KIR 3.4; KIR3.4; Potassium channel; Potassium channel inwardly rectifying subfamily J member 5; Potassium inwardly rectifying channel J5; Potassium inwardly rectifying channel subfamily J member 5.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學(xué)  通道蛋白  G蛋白信號(hào)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNJ5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008].

Function:
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium.

Subunit:
May associate with GIRK1 and GIRK2 to form a G-protein-activated heteromultimer pore-forming unit. The resulting inward current is much larger (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Islets, exocrine pancreas and heart.

DISEASE:
Defects in KCNJ5 are the cause of long QT syndrome type 13 (LQT13) [MIM:613485]. It is a heart disorder characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress, and can present with a sentinel event of sudden cardiac death in infancy.
Defects in KCNJ5 are the cause of familial hyperaldosteronism type 3 (FH3) [MIM:613677]. A form of hyperaldosteronism characterized by hypertension secondary to massive adrenal mineralocorticoid production. Like patients with familial hyperaldosteronism type 1 (glucocorticoid-remediable aldosteronism), patients with FH3 present with childhood hypertension, elevated aldosteronism levels, and high levels of the hybrid steroids 18-oxocortisol and 18-hydroxycortisol. However, hypertension and aldosteronism are not reversed by administration of exogenous glucocorticoids and patients require adrenalectomy to control hypertension.
Note=Somatic mutations in KCNJ5 have been found in aldosterone-producing adrenal adenomas and can be responsible for aldosteronism associated with cell autonomous proliferation. These are typically solitary, well circumscribed tumors diagnosed between ages 30 and 70. They come to medical attention due to new or worsening hypertension, often with hypokalemia. KCNJ5 mutations produce increased sodium conductance and cell depolarization, which in adrenal glomerulosa cells produces calcium entry, the signal for aldosterone production and cell proliferation.

Similarity:
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.

Database links:

Entrez Gene: 3762 Human

Entrez Gene: 16521 Mouse

Entrez Gene: 29713 Rat

Omim: 600734 Human

SwissProt: P48544 Human

SwissProt: P48545 Mouse

SwissProt: P48548 Rat

Unigene: 632109 Human

Unigene: 69472 Mouse

Unigene: 10047 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Involvement in disease; Defects in KCNJ5 are the cause of long QT syndrome type 13 (LQT13). It is a heart disorder characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause syncope and sudden death in response to excercise or emotional stress, and can present with a sentinel event of sudden cardiac death in infancy.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
一本色道久久综合亚洲精| 亚洲小说区图片区另类春色| 永久免费看A片无码网站宅男| 少妇BBW搡BBBB搡BBBB| 亚洲精品无码成人片久久不卡| 丁香五香天堂网| 哦┅┅快┅┅用力啊┅警花少妇| 少妇被多人C夜夜爽爽AV| 亚洲色成人网站WWW永久四虎 | JAPAN丰满人妻HDXXXX| 午夜精品一区二区三区在线观看| 国产又色又爽又高潮免费| 一区二区三区内射美女毛片| 久久亚洲国产成人精品无码区| 免费a级黄毛片| 黑人狂躁日本妞无码| 麻豆亚洲AV熟女国产一区二 | 欧洲AV无码放荡人妇网站| 凹凸国产熟女精品视频APP| 影音先锋资源站| 日韩GAY小鲜肉啪啪18禁| 最近国语视频在线观看免费播放| 国产999精品久久久久久| 少妇人妻丰满做爰XXX| 日本特黄特色aaa大片免费| 天干天干天啪啪夜爽爽99| JAPAN少妇洗澡VIDEOS| 精品无码一区二区三区| 乡下人产国偷V产偷V自拍| 日本老熟妇maturebbw| 小视频在线观看| 暖暖爱视频免费| 女人18片毛片60分钟| 久久久久噜噜噜亚洲熟女综合| 欧美乱大交XXXXX| 少妇又色又紧又爽又刺激视频| 亚州av| 被老外做的下身都肿了| 国产69精品久久久久| 无码精品一区二区三区| 久久久久亚洲AV无码专区喷水|