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Rabbit Anti-T4/L-Thyroxine/BF647 Conjugated antibody (bs-0706R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0706R-BF647
英文名稱1 Rabbit Anti-T4/L-Thyroxine/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的甲狀腺素T4抗體
別    名 Thyroxine 4; T4; Tg4; L-Thyroxine; Thyroxine; 3,3′,5,5″-Tetraiodo-L-thyronine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 信號(hào)轉(zhuǎn)導(dǎo)  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, )
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 0.77687kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from hu T4/L-Thyroxine
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Hormone produced by the thyroid glands to regulate metabolism by controlling the rate of oxidation in cells. Cases of hypothyroidism, where the gland is insufficiently active, can be treated by administration of thyroxine or a combination of thyroxine and triiodothyronine. L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.

Subcellular Location:
Secreted

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

甲狀腺素(Thyroxine, T4)是甲狀腺分泌最多的一種激素,血液中的T4全部由甲狀腺分泌而來,故血液中T4的濃度能很好地反應(yīng)甲狀腺功能狀態(tài)。正常情況下,血液中60%的T4與甲狀腺素結(jié)合球蛋白(TBG)結(jié)合,30%與甲狀腺素結(jié)合前蛋白(TBPA)結(jié)合,其余約10%與白蛋白結(jié)合,僅約0.03-0.04%呈游離狀態(tài)。由于T4與TBG親合力較高,所以血中T4的水平最易受到TBG的影響。
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