吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關于我們  聯(lián)系我們
中文字幕在线无码一区二区三区,EEUSS影院WWW在线观看,亚洲欧美成人AV在线观看
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-TFE3/PE Conjugated antibody (bs-8569R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8569R-PE
英文名稱1 Rabbit Anti-TFE3/PE Conjugated antibody
中文名稱 PE標記的轉(zhuǎn)錄因子E3
別    名 bHLH e33; bHLHe33; Class E basic helix-loop-helix protein 33; RCCP 2; RCCP2; Renal cell carcinoma, papillary; Tcfe 3; Tcfe3; TFE 3; Tfe3; TFE3_HUMAN; TFEA; Transcription factor binding to IGHM enhancer 3; Transcription factor E family, member A; Transcription factor E3; Transcription factor for IgH enhancer.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  轉(zhuǎn)錄調(diào)節(jié)因子  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 62kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TFE3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFE3 is ubiquitously expressed and can directly associates with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B-cell-specific gene transcription and DNA recombination. TFEB binds to the major late promoter of adenovirus and specifically associates with DNA as both a homodimer and a heterodimer with TFE3. TFEB is expressed at low levels in the embryo but at high levels in the trophoblast cells of the placenta, where it plays a critical role in regulating normal vascularization of the placenta. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. Unlike TFE3, the expression of TFEC is largely restricted to fibroblasts, myoblasts, chondrosarcoma cells, and myeloma cells.

Function:
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Subunit:
Homodimer and heterodimer; with TFEB or MITF.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous in fetal and adult tissues.

Post-translational modifications:
Sumoylated; does not affect dimerization with MITF. [DISEASE] Note=A chromosomal aberration involving TFE3 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with ASPSCR1 forms a ASPSCR1-TFE3 fusion protein.

DISEASE:
Note=A chromosomal aberration involving TFE3 is found in patients with alveolar soft part sarcoma. Translocation t(X;17)(p11;q25) with ASPSCR1 forms a ASPSCR1-TFE3 fusion protein.
Note=Chromosomal aberrations involving TFE3 are found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with PRCC; translocation t(X;1)(p11.2;p34) with PSF; inversion inv(X)(p11.2;q12) that fuses NONO to TFE3.

Similarity:
Belongs to the MiT/TFE family.
Contains 1 basic helix-loop-helix (bHLH) domain.

Database links:

Entrez Gene: 7030 Human

Entrez Gene: 209446 Mouse

Entrez Gene: 317376 Rat

Omim: 314310 Human

SwissProt: Q05B92 Cow

SwissProt: P19532 Human

SwissProt: Q64092 Mouse

Unigene: 249142 Mouse

Unigene: 9231 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
欧美大荫蒂AV高潮| ASS少妇PICS粉嫩BBW| 蜜臀AV在线播放一区二区三区| 老熟女重囗味HDXX70星空| 亚洲成AV人片一区二区密柚| 新狼窝色AV性久久久久久| 国产精品VA在线观看无码不卡| 在线精品国产一区二区三区 | 金瓶悔1一5扬思敏完整版| 国产猛男猛女超爽免费视频| 国产97色在线 | 日韩| 迷人的后妈韩国中文| 国产麻传媒精品国产AV| 老师穿着旗袍肉色丝袜让我玩| 欧美性猛交XXXX黑人| 中文字幕AV久久一区二区| 亚洲国产精品久久久久爰色欲| 成全动漫视频在线观看免费高清| 欧美ZC0O人与善交另类A片| 亚洲成AV人片一区二区密柚| 国产成人精品一区二区三区免费| 乳妓H军妓调教HH文| 欧美乱妇高清无乱码免费| 肉色超薄丝袜脚交一区二区| 男男暴菊GAY无套网站| 国产欧美熟妇另类久久久| 在线观看国产一区二区三区| 从卧室到厨房一直C| 亚洲∧V久久久无码精品| 国产又色又爽无遮挡免费| 老熟女高潮喷了一地| 人妻少妇精品无码专区二区| 亚洲大码熟女在线观看| 草草久久久无码国产专区| 精品爆乳一区二区三区无码AV| 国产成年无码久久久久毛片 | 办公室扒开奶罩揉吮奶头A片口述| 日产精品久久久久久久| 中文字幕欧美人妻精品一区| 国产在线精品一区二区| 国产午夜精品一区二区三区|