| 產(chǎn)品編號(hào) | bs-9541R-BF488 |
| 英文名稱1 | Rabbit Anti-Orai2/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的跨膜蛋白Orai2抗體 |
| 別 名 | C7orf19; CAP binding protein complex interacting protein 2; CBCIP 2; CBCIP2; Chromosome 7 open reading frame 19; FLJ12474; FLJ14733; FLJ44818; H_NH0514P08.8; Orai 2; ORAI calcium release activated calcium modulator 2; Protein orai 2; TMEM 142B; TMEM142B; Transmembrane protein 142B. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 通道蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Orai2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Orai2 is a 254 amino acid multi-pass membrane protein that belongs to the orai family of proteins. Localizing to the plasma membrane, Orai2 plays an important role in store-operated calcium (SOC) entry, a process involving Ca2+ influx and replenishment of Ca2+ stores formerly emptied through the action of inositol 1,4,5-trisphosphate production and other Ca2+ mobilizing agents. CRAC channels are responsible for medi-ating calcium influx in T-cells and play an important role in the immune response. Orai2 specifically increases the Ca2+-selective current through coaction with the Ca2+ sensor Stim1. Function: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1. Subunit: Interacts with EFCAB4B/CRACR2A. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the Orai family. Database links: Entrez Gene: 80228 Human Entrez Gene: 269717 Mouse Omim: 610929 Human SwissProt: Q96SN7 Human SwissProt: Q8BH10 Mouse Unigene: 363308 Human Unigene: 308396 Mouse Unigene: 18207 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
