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Rabbit Anti-C9orf86/BF647 Conjugated antibody (bs-9545R-BF647)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價

產(chǎn)品編號 bs-9545R-BF647
英文名稱1 Rabbit Anti-C9orf86/BF647 Conjugated antibody
中文名稱 BF647標記的9號染色體開放閱讀框86抗體
別    名 Chromosome 9 open reading frame 86; FLJ10101; Hypothetical protein LOC55684; KIAA1984; Parf; Partner of ARF; pp8875; Putative GTP binding protein Parf; Rab like GTP binding protein 1; Rab like GTP binding protein 1C; Rab like protein 1; RBEL1; RP11-216L13.9.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用 Flow-Cyt=2ug/Test ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human C9orf86
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
C9orf86 (Partner of ARF;PARF) binds p19(ARF), but not the p16(INK4A) isoform of CDKN2A. Knockdown of C9orf86 by RNA interference reduced the growth inhibitory activity of p19(ARF) and enhanced the rate of cell proliferation.

Function:
May enhance cellular proliferation. May reduce growth inhibitory activity of CDKN2A.

Subcellular Location:
Cytoplasmic and Nuclear. Note=Predominantly cytoplasmic. Proposed to shuttle between cytoplasm and nucleus.

Post-translational modifications:
Isoform 1 is O-glycosylated, while other isoforms are not.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:

Entrez Gene: 55684 Human

Entrez Gene: 227624 Mouse

Entrez Gene: 227624 Rat

Omim: 610615 Human

SwissProt: Q3YEC7 Human

SwissProt: Q5U3K5 Mouse

Unigene: 370555 Human

Unigene: 29600 Mouse

Unigene: 443064 Mouse

Unigene: 17709 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品圖片
Blank control:A431. Primary Antibody (green line): Rabbit Anti-C9orf86 antibody (bs-9545R-A647) Dilution: 2μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 90% ice-cold methanol for 20 min at-20℃. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.
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