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Rabbit Anti-Neprilysin 2/Gold Conjugated antibody (bs-11102R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-11102R-Gold
英文名稱1 Rabbit Anti-Neprilysin 2/Gold Conjugated antibody
中文名稱 膠體金標記的腦啡肽酶2抗體
別    名 Neprilysin-like Protease beta; Mel transforming oncogene like 1; Membrane metallo endopeptidase like 1; Membrane metallo endopeptidase like 2; MMEL1; Neprilysin2; Neprilysin-2; Neprilysin Like 1; MMEL2; NEPII; NL1; NL2; SEP; Soluble secreted endopeptidase.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 神經生物學  細胞粘附分子  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 89kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neprilysin 2 (451-550aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008].

Function:
Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond

Subcellular Location:
Membrane; Single pass type II membrane protein. Secreted.

Tissue Specificity:
Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.

Post-translational modifications:
N-glycosylated

Similarity:
Belongs to the peptidase M13 family.

Database links:
UniProtKB/Swiss-Prot: Q495T6.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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