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Rabbit Anti-PCDHA8/Cy5.5 Conjugated antibody (bs-11122R-Cy5.5)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11122R-Cy5.5
英文名稱1 Rabbit Anti-PCDHA8/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的原鈣粘附蛋白α8抗體
別    名 KIAA0345 like 6; PCDH ALPHA8; Protocadherin alpha 8; PCDA8_HUMAN; PCDH alpha 8; PCDH-alpha-8; Protocadherin alpha 8; Protocadherin alpha-8.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經(jīng)生物學  信號轉(zhuǎn)導  細胞粘附分子  細胞骨架  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHA8
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHA8 (protocadherin alpha 8) is a 950 amino acid single-pass type I membrane protein that contains six cadherin domains and is encoded by a gene which is located within the protocadherin alpha gene cluster on human chromosome 5. Existing as multiple alternatively spliced isoforms, PCDHA8 functions as a potential calcium-dependent cell adhesion protein that may be involved in the establishment and maintenance of neuronal connections within the brain.

Function:
PCDHA8 is most likely to play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. Two different isoforms are known.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein

Similarity:
Contains 6 cadherin domains.

Database links:

Entrez Gene: 56140 Human

Omim: 606314 Human

SwissProt: Q9Y5H6 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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