產(chǎn)品編號 | bs-11157R-Gold |
英文名稱1 | Rabbit Anti-PCDHGB4/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的原鈣粘蛋白γB4抗體 |
別 名 | Cadherin-20; Cadherin20; Cadherin 20; CDH20; FIB2; Fibroblast cadherin FIB2; Fibroblast cadherin-2; PCDGG_HUMAN; PCDH-gamma-B4; PCDHGB4; Protocadherin gamma subfamily B 4; Protocadherin gamma-B4. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞骨架 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 97kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PCDHGB4 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. Cadherin-20, also known as protocadherin gamma B4, is a member of the protocadherin gamma gene cluster. Expressed primariy in fibroblasts, cadherin-20 plays a critical role in neuronal cell-cell connections in the brain. Through its ability to mediate cell-cell adhesion, caderin-20 is thought to help the body respond to injury by regulating post-traumatic wound healing. Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subunit: Contains 6 cadherin domains. Subcellular Location: Cell membrane. Similarity: Contains 6 cadherin domains. Database links: Entrez Gene: 8641 Human Entrez Gene: 93701 Mouse UniProtKB/Swiss-Prot: Q9UN71.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |