吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
2022最新韩国理伦片在线观看,香蕉久久久久久AV成人,精品一区二区久久久久久久网站
Rabbit Anti-FIG4/APC Conjugated antibody (bs-11690R-APC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11690R-APC
英文名稱1 Rabbit Anti-FIG4/APC Conjugated antibody
中文名稱 APC標(biāo)記的肌萎縮側(cè)索硬化癥相關(guān)蛋白FIG4抗體
別    名 5-bisphosphate 5-phosphatase; Fig4; FIG4_HUMAN; KIAA0274; ALS11; Phosphatidylinositol 3; hSac3; Phosphatidylinositol 3,5 bisphosphate 5 phosphatase; Polyphosphoinositide phosphatase; SAC domain containing protein 3; SAC domain-containing protein 3; SAC3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Sheep, Monkey, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FIG4 (1-100aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008]

Function:
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2). In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide substrates in the order PtdIns(4,5)P2 > PtdIns(3,5)P2 > PtdIns(3,4,5)P3. Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.

Subcellular Location:
Endosome membrane. Localization requires VAC14 and PIKFYVE.

DISEASE:
Defects in FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) [MIM:611228]. CMT4J is a recessive demyelinating, severe form of Charcot-Marie-Tooth disease, the most common inherited disorder of the peripheral nervous system. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies characterized by severely reduced motor nerve conduction velocities (NCVs) (less than 38m/s) and segmental demyelination and remyelination, and primary peripheral axonal neuropathies characterized by normal or mildly reduced NCVs and chronic axonal degeneration and regeneration on nerve biopsy.
Defects in FIG4 are the cause of amyotrophic lateral sclerosis type 11 (ALS11) [MIM:612577]. ALS is a neurodegenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord, resulting in fatal paralysis. Sensory abnormalities are absent. Death usually occurs within 2 to 5 years. The etiology of amyotrophic lateral sclerosis is likely to be multifactorial, involving both genetic and environmental factors. The disease is inherited in 5-10%.

Similarity:
Contains 1 SAC domain.

Database links:

Entrez Gene: 9896 Human

Entrez Gene: 103199 Mouse

Entrez Gene: 309855 Rat

Omim: 609390 Human

SwissProt: Q92562 Human

SwissProt: Q91WF7 Mouse

Unigene: 529959 Human

Unigene: 277242 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
丰满少妇作爱视频免费观看| 性色AV无码不卡中文字幕| 国产激情精品一区二区三区| free性熟女妓女tube| 亚洲AV综合色区无码一二三区| 黑人巨大精品欧美一区二区免费| 无码毛片AAA在线| 亚洲女人被黑人巨大进入| 精品香蕉一区二区三区| 精品一区二区久久久久久久网站 | 国产特级毛片A片WWW| 少妇扒开腿让我爽了一夜| 欧美喷潮久久久XXXXX| 亚洲日韩精品欧美一区二区| 中文字幕人成无码人妻综合社区| 精品人体无码一区二区三区| 天堂网在线观看| 久久久久久国产精品免费免费男同| 日韩亚洲AV人人夜夜澡人人爽| 亚洲成AV人片在线观看| 中文字幕无码乱人伦| 国产精华液一线二线三线| 国产在线拍偷自揄拍无码成人小说 | 久久9精品区-无套内射无码| 国产特黄级AAAAA片免| 欧美AV在线观看| 亚洲熟女乱综合一区二区| 锕锕锕锕锕锕锕锕好疼好痛| 国产伦理一区二区| 久久精品AⅤ无码中文字字 | 久久99国产精品久久| 成人做爰WWW免费看视频日本| 国产精品美女午夜爽爽爽免费| 久久综合狠狠综合久久综合88| 老师说我考好了就随便我怎样| 久久久中日AB精品综合| 国产98色在线 | 日韩| 国产精品揄拍100视频| 中文字幕被公侵犯的漂亮人妻| free性熟女妓女tube| 一本一道AV无码中文字幕|