吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
天美传媒免费观看一二三在线,日韩乱码人妻无码中文字幕久久
Rabbit Anti-phospho-AMPK beta 1 (Ser108)/PE-Cy5 Conjugated antibody (bs-3026R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3026R-PE-Cy5
英文名稱1 Rabbit Anti-phospho-AMPK beta 1 (Ser108)/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的磷酸化腺苷單磷酸活化蛋白激酶β1抗體
別    名 PRKAB1(phospho S108); PRKAB1(phospho-S108); AMPK beta 1(Ser108); p-AMPK beta 1(Ser108); p-AMPK beta 1(S108); 5 AMP activated protein kinase subunit beta 1; AMPK; AMPK beta 1 chain; AMPKb; HAMPKb; PRKAB1; 5'-AMP-activated protein kinase subunit beta-1; AMP-activated protein kinase beta subunit; protein kinase, AMP-activated, noncatalytic, beta-1; AMPK beta -1 chain; 5'-AMP-activated protein kinase beta-1 subunit; AMPKb; AMPK subunit beta-1; AAKB1_RAT; AAKB1_HUMAN; AMPK b1; AMPK-b1.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  染色質(zhì)和核信號(hào)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat, 
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 30kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from rat AMPK beta 1 around the phosphorylation site of Ser108
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].

Function:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

Subunit:
AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.

Tissue Specificity:
Highly expressed in kidney, heart, white adipose tissue, lung and spleen.

Post-translational modifications:
Phosphorylated when associated with the catalytic subunit (PRKAA1 or PRKAA2). Phosphorylated by ULK1; leading to negatively regulate AMPK activity and suggesting the existence of a regulatory feedback loop between ULK1 and AMPK.

Similarity:
Belongs to the 5'-AMP-activated protein kinase beta subunit family.

Database links:

Entrez Gene: 5564 Human

Entrez Gene: 19079 Mouse

Entrez Gene: 83803 Rat

Omim: 602740 Human

SwissProt: Q9Y478 Human

SwissProt: Q9R078 Mouse

SwissProt: P80386 Rat

Unigene: 6061 Human

Unigene: 726001 Human

Unigene: 458152 Mouse

Unigene: 3619 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

AMPKβ1(AMP-activated Protein Kinase beta-1)(腺苷單磷酸活化蛋白激酶β-1)是一種參與細(xì)胞適應(yīng)能量危機(jī)的應(yīng)激反應(yīng)酶,AMPK不僅可以在細(xì)胞水平作為能量的感受器,還可以通過激素和細(xì)胞因子,如瘦素、脂聯(lián)素和ghrelin來參與調(diào)節(jié)機(jī)體的能量消耗和能量攝入.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
学长被C哭着爬走又被拉回来 | 宝宝好涨水快流出来免费视频| 精品一区二区久久久久久久网站| 亚洲国产精华液2020| 日韩无码专区| 欧美乱妇高清无乱码免费| 粉嫩名器少妇名器| B站禁止转播404入口| 国产偷窥熟妇高潮呻吟| 五月丁香综合啪啪成人小说| WWW夜插内射视频网站| 公与淑婷厨房猛烈进出视频| 无码人妻熟妇AV又粗又大| 人人爽久久涩噜噜噜AV| 重口老太大和小伙乱| 午夜福利电影 | 色午夜| A片扒开双腿进入做爽爽| FREE性VIDEO西欧极品| chinesemature老熟妇高潮| 熟女肥臀白浆大屁股一区二区 | 亚洲精品99久久久久中文字幕| 国产无遮挡A片又黄又爽| 99精产国品一二三产区| 推特APP下载| 天天做天天爱夜夜爽| 邻居少妇张开双腿让我爽一夜 | 久久久久久国产精品免费免费男同| 国产午夜精品一区二区三区| 欧美一区二区三区成人片在线| 无码人妻一区二区三区精品视频| 中文字幕乱码人妻一区二区三区| BGMBGMBGM毛多多视频| 国产免费观看久久黄AV片| 国产手机精品一区二区| 粉嫩名器少妇名器| 色一情一乱一伦一区二区三区 | 少妇人妻系列1~100| 麻豆国产尤物AV尤物在线观看 | av片在线播放| 亚洲精品午夜国产VA久久成人|