吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲AV永久无码一区二区三区,激情 小说 亚洲 图片 伦,CHINESE熟女老女人HD
Rabbit Anti-Phospho-Caspase-9 (Tyr153)/Cy5.5 Conjugated antibody (bs-3083R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3083R-Cy5.5
英文名稱1 Rabbit Anti-Phospho-Caspase-9 (Tyr153)/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的磷酸化半胱氨酸蛋白酶9抗體
別    名 APAF 3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease activating factor 3; Apoptotic protease Mch 6; CASP 9; CASP9; Caspase 9 Dominant Negative; Caspase 9 precursor; Caspase 9c; Caspase9; EC 3.4.22.; ICE LAP6; ICE like apoptotic protease 6; MCH6 antibody RNCASP9; CASP9_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, 
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Subunit:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin.

Tissue Specificity:
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.

Post-translational modifications:
Cleavages at Asp-315 by granzyme B and at Asp-330 by caspase-3 generate the two active subunits. Caspase-8 and -10 can also be involved in these processing events.
Phosphorylated at Thr-125 by MAPK1/ERK2. Phosphorylation at Thr-125 is sufficient to block caspase-9 processing and subsequent caspase-3 activation.

Similarity:
Belongs to the peptidase C14A family.
Contains 1 CARD domain.

Database links:

Entrez Gene: 842 Human

Entrez Gene: 12371 Mouse

Entrez Gene: 58918 Rat

Omim: 602234 Human

SwissProt: P55211 Human

SwissProt: Q4FJK5 Mouse

SwissProt: Q920G4 Rat

Unigene: 329502 Human

Unigene: 88829 Mouse

Unigene: 32199 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Caspase-9半胱氨酸蛋白酶家族成員之一,又稱ICE-Lap6(ICE Like apoptotease 6)參與細(xì)胞凋亡過程和細(xì)胞因子的加工過程,在許多胚胎和成人組織中都有分布。此抗體主要用于腫瘤凋亡的研究。
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
性色AV一区二区三区| 巨胸爆乳美女露双奶头挤奶| AAA级久久久精品无码片 | 香蕉久久夜色精品升级完成| 亚洲欧美一区二区三区在线| 99精品人妻少妇一区二区| 国产精品久久久久AV| 公与淑婷厨房猛烈进出视频| GOGOGO高清在线观看视频| 亚洲成AV人片在线观看无 | 亚洲精品久久激情国产片| 亚洲爆乳无码精品AAA片蜜桃| 免费高清理伦片A片在线观看| 秘书被老板CAO到合不拢腿| 国产偷v国产偷v亚洲高清| 国产真人无码作爱视频免费| 亚洲2022国产成人精品无码区| 国产成人午夜精品久久久久久| 亚洲熟女少妇一区二区| 人妻精油按摩BD高清中文字幕| 国内精品卡一卡二卡三| 精品少妇人妻AV一区二区三区 | 精品久久久久久亚洲综合网| 神马影院| 14妺妺让我破了她的处| 久久久久亚洲AV无码A片下载| 老旺的大肉蟒进进出出| 国产男女做爰猛烈叫床小说| 亚洲av无码乱码在线观看性色| 蜜臀AV色欲A片无码精品一区| 少妇激情一区二区三区视频| 日本免费无码一区二区到五区| 丁香色欲久久久久久综合网| 天堂√最新版中文在线| 妈妈的朋友在线| 疯狂做受XXXX高潮欧美日本| 亚洲AV无码一区二区三区性色| 顶级少妇做爰视频在线观看| 后入内射无码人妻一区| 少妇寂寞偷公乱400章深夜书屋| 国产乱自产黄A片在线观看|