吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
灭蟑螂土办法,全部孕妇毛片丰满孕妇孕交,99无码熟妇丰满人妻啪啪
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Phospho-Connexin 43 (Ser368)/BF350 Conjugated antibody (bs-3098R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3098R-BF350
英文名稱1 Rabbit Anti-Phospho-Connexin 43 (Ser368)/BF350 Conjugated antibody
中文名稱 BF350標記的磷酸化Connexin 43蛋白抗體
別    名 Connexin 43(phospho-Ser368); Connexin 43(phospho Ser368); Connexin 43(phospho S368); Connexin 43; Connexin43v Cx 43v CX43; DFNB38; Gap junction 43 kDa heart protein;Connexin-43; Gap junction alpha 1 protein; Gap junction protein alpha 1 43kDa (connexin 43); Gap junction protein alpha 1 43kDa; Gap junction protein alpha like; GJA 1; GJA1; GJA-1; GJAL; HGNC:4282; HGNC:8112; Oculodentodigital dysplasia; ODD; ODOD; SDTY3; Syndactyly type III; CXA1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 心血管  細胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Cow, Monkey, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Connexin 43 around the phosphorylation site of Ser368
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia and heart malformations. [provided by RefSeq].

Function:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract.

Subunit:
A connexon is composed of a hexamer of connexins. Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain). Interacts with UBQLN4. Interacts with SGSM3. Interacts with KIAA1432/CIP150. Interacts with CNST and CSNK1D.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Expressed in the heart and fetal cochlea.

Post-translational modifications:
Phosphorylated at Ser-368 by PRKCG; phosphorylation induces disassembly of gap junction plaques and inhibition of gap junction activity. Phosphorylation at Ser-325, Ser-328 and Ser-330 by CK1 modulates gap junction assembly.

DISEASE:
Defects in GJA1 are the cause of autosomal dominant oculodentodigital dysplasia (ODDD) [MIM:164200]; also known as oculodentoosseous dysplasia. ODDD is a highly penetrant syndrome presenting with craniofacial (ocular, nasal, dental) and limb dysmorphisms, spastic paraplegia, and neurodegeneration. Craniofacial anomalies tipically include a thin nose with hypoplastic alae nasi, small anteverted nares, prominent columnella, and microcephaly. Brittle nails and hair abnormalities of hypotrichosis and slow growth are present. Ocular defects include microphthalmia, microcornea, cataracts, glaucoma, and optic atrophy. Syndactyly type 3 and conductive deafness can occur in some cases. Cardiac abnormalities are observed in rare instances.

Similarity:
Belongs to the connexin family. Alpha-type (group II) subfamily.

Database links:

Entrez Gene: 2697 Human

Entrez Gene: 281193 Cow

Entrez Gene: 403418 Dog

Entrez Gene: 14609 Mouse

Entrez Gene: 24392 Rat

Omim: 121014 Human

SwissProt: P18246 Cow

SwissProt: Q6S9C0 Dog

SwissProt: P17302 Human

SwissProt: P23242 Mouse

SwissProt: Q6TYA7 Rabbit

SwissProt: P08050 Rat

Unigene: 74471 Human

Unigene: 378921 Mouse

Unigene: 10346 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

間隙連接蛋白-43(Gap junction alpha-1 protein; GJA-1; (Vascular smooth muscle connexin-43))是構(gòu)成細胞間的通道,小分子成份可以借此在細胞間擴散。Connexin-43也是心肌縫隙連接的主要蛋白之一。
此外,星形細胞、成纖維細胞、平滑肌和腎等組織也有表達Connexin 43.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
三妻四妾免费观看完整版高清| 国产成人午夜精品久久久久久| 国产精品一卡二卡三卡| 国产精品永久免费| 欧美性猛交XXXX| 精品人妻人人做人人爽夜夜爽| 粗大挺进朋友人妻身体里国产电影 | 女警察双腿大开呻吟| 国语熟妇乱人乱A片久久| 国产无套内射普通话对白| XX性欧美肥妇精品久久久久久| 国产AV无码专区亚洲AV麻豆| 国产成人无码AA精品一区| 日本夜爽爽一区二区三区| 欧美老妇交乱视频在线观看 | 国产亚洲AV无码AV男人的天堂| 又爆又大又粗又硬又黄的A片| 亚洲熟妇AV日韩熟妇在线| 国产美女裸体无遮挡免费视频| 小鸡庄园每日答案汇总| 波多野结衣中文字幕一区二区三区| 亚洲精品白浆高清久久久久久| 中文字幕无码精品亚洲资源网久久 | 国产超碰人人模人人爽人人添| 无码人妻久久一区二区三区免费丨| 欧美疯狂做受XXXXX高潮| CHINESE性内射高清国产| 黑人狂躁日本妞无码| 亚洲精品无码久久久久秋霞| 久久精品AⅤ无码中文字字幕重口| 国产精品久久毛片| CHINESE性内射高清国产 | 亚洲精品乱码久久久久久蜜桃不卡 | 亚洲AV无码专区在线观看下载| 国产成人精品久久| 亚洲精品乱码久久久久久不卡| 日韩A片无码毛片免费看小说| 国产伦理一区二区| 国产AV无码专区亚洲AV毛片搜 | 日本理论片| 偷窥 性别 瘾 XXXXX|