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Rabbit Anti-phospho-Ephrin B (Tyr329)/PE-Cy5.5 Conjugated antibody (bs-3217R-PE-Cy5.5)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3217R-PE-Cy5.5
英文名稱1 Rabbit Anti-phospho-Ephrin B (Tyr329)/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的磷酸化Ephrin B抗體
別    名 Ephrin B (phospho Y329); p-Ephrin B (phospho Y329); phospho-Ephrin B1 (Tyr329); phospho-Ephrin B2(Tyr316); CEK5 ligand; EFNB1; ELK L; EphrinB; Ephrin-B; ELK ligand; ELKL; EPH related receptor tyrosine kinase ligand 2; Ephrin B Precursor; Ephrin B1; Ephrin B2; LERK 2; LERK2; EFNB1_HUMAN; EFNB2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細(xì)胞生物  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 34kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Ephrin B around the phosphorylation site of Tyr329
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.

Subunit:
Interacts with GRIP1 and GRIP2. Binds to Nipah virus G protein.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in brain; expressed in embryonic floor plate, roof plate and hindbrain segments.

Similarity:
Belongs to the ephrin family.
Contains 1 ephrin RBD (ephrin receptor-binding) domain.

Database links:

Entrez Gene: 1947 Human

Entrez Gene: 1948 Human

Entrez Gene: 13641 Mouse

Entrez Gene: 13642 Mouse

Entrez Gene: 25186 Rat

Omim: 300035 Human

Omim: 600527 Human

SwissProt: P52799 Human

SwissProt: P98172 Human

SwissProt: P52795 Mouse

SwissProt: P52800 Mouse

SwissProt: P52796 Rat

SwissProt: Q6P7B6 Rat

Unigene: 144700 Human

Unigene: 149239 Human

Unigene: 44398 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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