產(chǎn)品編號 | bs-3156R-Gold |
英文名稱1 | Rabbit Anti-phospho-GCN2 (Thr667)/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的磷酸化蛋白激酶GCN2蛋白抗體 |
別 名 | GCN2 (phospho T667); p-GCN2 (phospho T667); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
產(chǎn)品類型 | 磷酸化抗體 |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Dog, Cow, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 181kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human GCN2 around the phosphorylation site of Thr667 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses. Tissue Specificity: Widely expressed. Post-translational modifications: Autophosphorylated on threonine residues. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily. Contains 2 protein kinase domains. Contains 1 RWD domain. Database links: Entrez Gene: 440275 Human Entrez Gene: 27103 Mouse Omim: 609280 Human SwissProt: Q9P2K8 Human SwissProt: Q9QZ05 Mouse Unigene: 656673 Human Unigene: 217616 Mouse Unigene: 8333 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. GCN2蛋白的作用;可能是將短期記憶變成長期記憶的一個(gè)主控調(diào)節(jié)因子, GCN2蛋白在長期記憶形成中功能的發(fā)現(xiàn)將可能幫助研究人員開發(fā)出提高記憶力喪失的病人提高記憶力。 |