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Rabbit Anti-Phospho-FRA1 (Ser265)/AP Conjugated antibody (bs-3158R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3158R-AP
英文名稱1 Rabbit Anti-Phospho-FRA1 (Ser265)/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的磷酸化FRA-1蛋白抗體
別    名 FOSL1; Fos related antigen 1; FOS L1; FOS like antigen 1; FOSL 1; FOSL1 protein; FRA 1; Fos-related antigen 1; FOSL1_HUMAN; FRA-1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
產(chǎn)品類(lèi)型 磷酸化抗體 
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 28kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human FRA1 around the phosphorylation site of Ser265
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq].

Subunit:
Heterodimer.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. Fos subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

Database links:

Entrez Gene: 8061 Human

Omim: 136515 Human

SwissProt: P15407 Human

Unigene: 283565 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

FOSL1蛋白對(duì)細(xì)胞因子、生長(zhǎng)因子、感染或致癌刺激等生理或病理信號(hào)發(fā)生應(yīng)答,調(diào)節(jié)基因的轉(zhuǎn)錄, 參與細(xì)胞的增殖、分化等過(guò)程。 FOSL1在腫瘤形成及發(fā)展過(guò)程中, 通過(guò)促進(jìn)細(xì)胞增殖、抑制分化、促進(jìn)腫瘤細(xì)胞的侵襲和轉(zhuǎn)移等過(guò)程發(fā)揮作用。
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