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Rabbit Anti-prox1/HRP Conjugated antibody (bs-2774R-HRP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-2774R-HRP
英文名稱(chēng)1 Rabbit Anti-prox1/HRP Conjugated antibody
中文名稱(chēng) 辣根過(guò)氧化物酶標(biāo)記的prox-1抗體
別    名 Homeobox prospero like protein; Homeobox prospero like protein PROX1; Prospero related homeobox 1;prox-1; PROX 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 心血管  免疫學(xué)  神經(jīng)生物學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human prox-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Prox1 is a prospero-related homeobox gene. Its expression pattern suggests it has a role in a variety of embryonic tissues and may play a fundamental role in early development of the CNS. It may regulate gene expression and the development of postmitotic undifferentiated young neurons.

Subcellular Location:
Nucleus.

Tissue Specificity:
Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas.

Database links:

Entrez Gene: 395802 Chicken

Entrez Gene: 5629 Human

Entrez Gene: 19130 Mouse

Entrez Gene: 305066 Rat

Entrez Gene: 399348 Xenopus laevis

Entrez Gene: 30679 Zebrafish

Omim: 601546 Human

SwissProt: Q91018 Chicken

SwissProt: Q92786 Human

SwissProt: P48437 Mouse

Unigene: 741808 Human

Unigene: 744931 Human

Unigene: 132579 Mouse

Unigene: 392678 Mouse

Unigene: 26557 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

prox-1主要表達(dá)于晶狀體、心臟、肝臟、胰腺和神經(jīng)系統(tǒng)等的非內(nèi)皮細(xì)胞,在成人正常組織、胚胎淋巴管內(nèi)皮細(xì)胞或腫瘤組織的淋巴內(nèi)皮細(xì)胞上也可檢測(cè)到。移除prox-1基因后,胚胎發(fā)育時(shí)原始靜脈內(nèi)皮細(xì)胞生成淋巴管過(guò)程被阻斷,表明prox-1是淋巴管生成最基本的調(diào)控因子.
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