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Rabbit Anti-Hes5/BF350 Conjugated antibody (bs-3767R-BF350)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3767R-BF350
英文名稱1 Rabbit Anti-Hes5/BF350 Conjugated antibody
中文名稱 BF350標記的發(fā)狀分裂相關增強子-5抗體
別    名 Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  信號轉導  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Hes5 (28-100aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008]

Function:
Transcriptional repressor of genes that require a bHLH protein for their transcription

Subunit:
Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in fetal heart and brain tumors.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 Orange domain.

Database links:

Entrez Gene: 388585 Human

Entrez Gene: 15208 Mouse

Entrez Gene: 79225 Rat

SwissProt: Q5TA89 Human

SwissProt: P70120 Mouse

SwissProt: Q03062 Rat

Unigene: 57971 Human

Unigene: 137268 Mouse

Unigene: 22422 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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