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Rabbit Anti-Dopamine beta Hydroxylase/HRP Conjugated antibody (bs-0596R-HRP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0596R-HRP
英文名稱1 Rabbit Anti-Dopamine beta Hydroxylase/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的多巴胺β羥化酶抗體
別    名 DBH; DBM; Dopamine beta hydroxylase; Dopamine-Beta-Hydroxylase; Dopamine beta monooxygenase; DOPO_RAT; DOPO_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  神經(jīng)生物學(xué)  合成與降解  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DBH
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Dopamine-beta-Hydroxylase (DBH), Dopamine can be transformed into Noradrenalin. Conversion of dopamine to noradrenaline. [SUBUNIT] Homotetramer composed of two non-covalently bound disulfide-linked dimers. [SUBCELLULAR LOCATION] Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (Potential). Belongs to the copper type II ascorbate-dependent monooxygenase family.

Function:
Conversion of dopamine to noradrenaline.

Subunit:
Homotetramer composed of two non-covalently bound disulfide-linked dimers (By similarity).

Subcellular Location:
Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen (By similarity).
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type II membrane protein (By similarity). Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass type II membrane protein (By similarity).

Tissue Specificity:
Chromaffin granules of the adrenal medulla and synaptic vesicles of the sympathetic nervous system.

Similarity:
Belongs to the copper type II ascorbate-dependent monooxygenase family.
Contains 1 DOMON domain.

Database links:

Entrez Gene: 280758 Cow

Entrez Gene: 1621 Human

Entrez Gene: 13166 Mouse

Entrez Gene: 25699 Rat

Omim: 223360 Human

Omim: 609312 Human

SwissProt: P15101 Cow

SwissProt: P09172 Human

SwissProt: Q64237 Mouse

SwissProt: Q05754 Rat

Unigene: 223858 Human

Unigene: 591890 Human

Unigene: 167781 Mouse

Unigene: 87166 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Dopamine-β-Hydroxylase(DBH)—多巴胺β羥化酶??梢詫⒍喟桶忿D(zhuǎn)化成去甲腎上腺素。是腎上腺素能神經(jīng)元的標(biāo)志。
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