吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
24小时日本在线WWW免费的,亚洲 欧美 激情 小说 另类
Rabbit Anti-NUMB/BF350 Conjugated antibody (bs-3510R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3510R-BF350
英文名稱1 Rabbit Anti-NUMB/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的膜相關(guān)蛋白Numb抗體
別    名 c14_5527; C14orf41; FLJ31314; h Numb; h-Numb; Numb; Numb homolog (Drosophila); Numb homolog; Numb protein homolog; NUMB_HUMAN; Protein numb homolog; Protein S171; S171.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  干細(xì)胞  細(xì)胞膜受體  細(xì)胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NUMB
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Function:
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Subunit:
Interacts with CDH1 and TFAP2B (By similarity). Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis.

Subcellular Location:
Membrane; Peripheral membrane protein.

Post-translational modifications:
Phosphorylated on Ser-276 and Ser-295 by CaMK1.
Isoform 1 and isoform 2 are ubiquitinated by LNX leading to their subsequent proteasomal degradation. Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.

Similarity:
Contains 1 PID domain.

Database links:

Entrez Gene: 8650 Human

Entrez Gene: 18222 Mouse

Entrez Gene: 29419 Rat

Omim: 603728 Human

SwissProt: P49757 Human

SwissProt: Q9QZS3 Mouse

SwissProt: Q2LC84 Rat

Unigene: 654609 Human

Unigene: 714879 Human

Unigene: 4390 Mouse

Unigene: 102078 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

膜相關(guān)蛋白Numb是細(xì)胞命運(yùn)決定因子:在細(xì)胞有絲分裂期,Numb選擇性地分布于細(xì)胞的一側(cè),在胞質(zhì)分裂后則被分配于一個(gè)子細(xì)胞,Numb通過抑制跨膜受體Notch而發(fā)揮作用, Numb信號(hào)途徑在前體細(xì)胞的神經(jīng)元調(diào)控方面起著重要作用.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国精产品一区二区三区有限公司| 亚欧洲精品在线视频免费观看| 荫蒂每天被三个男人添视频| 熟妇人妻系列AV无码一区二区| 中文字幕欧美人妻精品一区| 无码人妻丰满熟妇精品区| 成人夜色视频网站在线观看| 国产人妖乱国产精品人妖| 人妻少妇无码精品视频区| 免费看片A级毛片免费看| 欧美,日韩在线视频| 99久久精品费精品蜜臀AV| 国产情侣一区二区| 白洁被高振干到九点多| 中文字幕人妻丝袜乱一区三区| 99精产国品一二三产区区别电影| 又硬又粗又大一区二区三区视频 | 国产精久久一区二区三区| 夜里十大禁用直播APP| 国产精品第一页| 老熟女高潮一区二区三区| 久久精品国产亚洲AV高清色欲| 无码熟熟妇丰满人妻啪啪| 国产精品自产拍高潮在线观看| 新岳乱合集500系列| 国精无码欧精品亚洲一区| 人人妻人人澡人人爽人人精品| 国产精品爽黄69天堂A片| 国产精品一区二区久久| CAOPOREN免费精品视频| 精品无码一区二区三区爱欲| 国产精品沙发午睡系列990531| 波多野结AV衣东京热无码专区| 中文字幕精品久久久久人妻 | 日本人妻丰满熟妇久久久久久 | 人妻丝袜无码国产一区| 日本动漫瀑乳H动漫啪啪免费| 羞羞漫画官网| 亚洲日韩一区二区三区| 婷婷人人爽人人爽人人片| 久久精品无码AV|