吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
公妇借种乱H日出水了,精品人妻无码区二区三区
Rabbit Anti-DVL1/Biotin Conjugated antibody (bs-0598R-Bio)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-0598R-Bio
英文名稱(chēng)1 Rabbit Anti-DVL1/Biotin Conjugated antibody
中文名稱(chēng) 生物素標(biāo)記的蓬亂蛋白1抗體
別    名 Dishevelled 1; Dishevelled; Dishevelled dsh homolog 1; Dishevelled1; DSH homolog 1; Dvl; MGC54245; Segment polarity protein dishevelled homolog DVL 1; Segment polarity protein dishevelled homolog DVL1; DVL1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DVL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DVL1 may play a role in the signal transduction pathway mediated by multiple Wnt genes. [Subunit] Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts (via PDZ domain) with NXN (By similarity). Interacts with CXXC4. [Subcellular Location] Cytoplasm (Potential). Belongs to the DSH family.

Function:
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Subunit:
Interacts with CXXC4. Interacts (via PDZ domain) with NXN (By similarity). Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts with ARRB1; the interaction is enhanced by phosphorylation of DVL1. Interacts with CYLD (By similarity). Interacts (via PDZ domain) with RYK. Self-associates (via DIX domain) and forms higher homooligomers. Interacts (via PDZ domain) with DACT1 and FZD7, where DACT1 and FZD7 compete for the same binding site (By similarity). Interacts (via DEP domain) with MUSK; the interaction is direct and mediates the formation a DVL1, MUSK and PAK1 ternary complex involved in AChR clustering (By similarity).

Subcellular Location:
Cell membrane. Cytoplasm, cytosol. Cytoplasmic vesicle. Localizes at the cell membrane upon interaction with frizzled family members.

Post-translational modifications:
Ubiquitinated; undergoes both 'Lys-48'-linked ubiquitination, leading to its subsequent degradation by the ubiquitin-proteasome pathway, and 'Lys-63'-linked ubiquitination. The interaction with INVS is required for ubiquitination. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.

Similarity:
Belongs to the DSH family.
Contains 1 DEP domain.
Contains 1 DIX domain.
Contains 1 PDZ (DHR) domain.

Database links:

Entrez Gene: 1855 Human

Entrez Gene: 13542 Mouse

Entrez Gene: 83721 Rat

Omim: 601365 Human

SwissProt: Q5IS48 Chimpanzee

SwissProt: O14640 Human

SwissProt: P51141 Mouse

SwissProt: Q9WVB9 Rat

Unigene: 741165 Human

Unigene: 3400 Mouse

Unigene: 144610 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

dishevelled-1蓬亂蛋白-1主要用于神經(jīng)退行性改變-AD病方面的研究.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲AV午夜成人片精品网站| 女人下边被添全过视频| 亚洲AV无码国产精品色软件| 三男一女做2爱A片免费视频| 国产产无码乱码精品久久鸭| 国产片XXXXA片国语对白| 含着奶头搓揉深深挺进| 亚洲欧美自偷自拍另类小说| 无码性午夜视频在线观看| 999国产精品999久久久久久| 午夜精品久久久内射近拍高清| (无码视频)在线观看| 亚洲成熟丰满熟妇高潮xxxxx | 国产大屁股喷水视频在线观看| 国产精品永久久久久久久久久| 无码人妻一区二区三区免费N鬼沢 久久精品色妇熟妇丰满人妻5O | 挺进邻居丰满少妇的身体| 日韩A片无码毛片免费看小说| 超薄肉色丝袜一区二区| 人妻无码一区二区三区| 日韩欧美亚洲国产精品字幕久久久| 色琪琪女色窝77777| 金瓶悔1一5扬思敏完整版| 人人添人人妻人人爽夜欢视AV| 免费无码国产欧美久久18| 久久夜色精品国产噜噜亚洲AV| 夜夜嗨AV一区二区三区| 中文无码精品一区二区三区| 国产成人亚洲精品| 久久人人爽人人爽人人AV东京热| 99久久精品费精品蜜臀AV| 老司机午夜免费精品视频| 久久97精品久久久久久久不卡| 久久久久久国产精品免费免费| 国产在线拍偷自揄拍无码成人小说 | 国产婷婷色一区二区三区| 玩弄高耸白嫩的乳峰A片| 黑人上司粗大拔不出来电影 | 精品动漫国产亚洲AV在线观看| 实拍各种胸走光见奶头| 亚洲AV无码久久寂寞少妇|