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扒开腿狂躁女人爽出白浆 ,疯狂的肥岳交换130部小短片
Rabbit Anti-Radixin/Biotin Conjugated antibody (bs-3808R-Bio)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-3808R-Bio
英文名稱1 Rabbit Anti-Radixin/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的根蛋白抗體
別    名 ESP10; Hh-induced MATH and BTB domain-containing protein; HIB; Moesin-B; Protein roadkill; Radixin; rdx; CB567; CG12537; DFNB24; RADI_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞表面分子  上皮細(xì)胞  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 69kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Radixin
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Function:
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane.

Subunit:
Binds SLC9A3R1. Interacts with NHERF1, NHERF2, LAYN, MME/NEP and ICAM2

Subcellular Location:
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Note=Highly concentrated in the undercoat of the cell-to-cell adherens junction and the cleavage furrow in the interphase and mitotic phase, respectively.

Post-translational modifications:
Phosphorylated by tyrosine-protein kinases. Phosphorylation by ROCK2 suppresses the head-to-tail association of the N-terminal and C-terminal halves resulting in an opened conformation which is capable of actin and membrane-binding

DISEASE:
Defects in RDX are the cause of deafness autosomal recessive type 24 (DFNB24) [MIM:611022]. DFNB24 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Similarity:
Contains 1 FERM domain.

Database links:

Entrez Gene: 5962 Human

Entrez Gene: 19684 Mouse

Entrez Gene: 315655 Rat

Omim: 179410 Human

SwissProt: P35241 Human

SwissProt: P26043 Mouse

Unigene: 263671 Human

Unigene: 592679 Human

Unigene: 245746 Mouse

Unigene: 472057 Mouse

Unigene: 224619 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

根蛋白是一種細(xì)胞骨架蛋白,在連接肌動(dòng)蛋白于質(zhì)膜中可能有重要作用。研究表明,根蛋白對(duì)于結(jié)合膽紅素通過(guò)其Mrp2在BCMs中定位支持的分泌是需要的。埃茲蛋白-根蛋白-膜突蛋白家族蛋白是亞膜皮質(zhì),特別是上皮細(xì)胞中普遍存在的成分。其可能參與將肌動(dòng)蛋白絲的頂端錨定于胞膜。
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