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Rabbit Anti-TNFRSF19/PE Conjugated antibody (bs-3852R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-3852R-PE
英文名稱1 Rabbit Anti-TNFRSF19/PE Conjugated antibody
中文名稱 PE標(biāo)記的腫瘤壞死因子配體超家族成員19抗體
別    名 TROY; TAJ alpha; TAJ; TNFRSF 19; TNFRSF19; Tnfrsf20; Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  生長因子和激素  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, G)
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 43kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TROY C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
TROY is a member of the TNF receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate the JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Subunit:
Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.

Similarity:
Contains 3 TNFR-Cys repeats.

Database links:

Entrez Gene: 55504 Human

Entrez Gene: 29820 Mouse

Omim: 606122 Human

SwissProt: Q9NS68 Human

SwissProt: Q9JLL3 Mouse

Unigene: 149168 Human

Unigene: 730848 Human

Unigene: 281356 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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