| 產(chǎn)品編號(hào) | bs-0455R-Gold |
| 英文名稱1 | Rabbit Anti-HSL/LIPE/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的荷爾蒙敏感脂肪酶抗體 |
| 別 名 | Hormone sensitive lipase; hormone-sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE; Hormone-sensitive lipase; LIPS_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 心血管 免疫學(xué) 生長(zhǎng)因子和激素 糖尿病 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Fruit Fly, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 116kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from rat HSL N-terminus |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: HSL ( hormone- sensitive lipase ) is an enzyme involved in hydrolysis of stored triglycerides and fatty acids; important for regulation of energy homeostasis. It has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. Function: In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. Subunit: Interacts with PTRF in the adipocyte cytoplasm. Subcellular Location: Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Similarity: Belongs to the 'GDXG' lipolytic enzyme family. Database links: Entrez Gene: 3991 Human Entrez Gene: 16890 Mouse Omim: 151750 Human SwissProt: Q05469 Human SwissProt: Q6NSL7 Human SwissProt: P54310 Mouse Unigene: 656980 Human Unigene: 158548 Mouse Unigene: 333679 Mouse Unigene: 10566 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HSL又稱：敏感性甘油三酯脂肪酶，在脂肪動(dòng)員中，脂肪細(xì)胞內(nèi)激素敏感性甘油三酯脂肪酶（HSL）起決定性作用，它是脂肪分解的限速酶，稱為激素敏感性脂肪酶。 腎上腺素、去甲腎上腺素、胰高血糖素等激活HSL促進(jìn)脂肪動(dòng)員；胰島素，前列腺素E及煙酸等抑制HSL，抑制脂肪的動(dòng)員。 |
