吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  人才招聘  關于我們  聯(lián)系我們
国产AV无码专区亚洲AV麻豆,肉妇春潮干柴烈火MYFDUCC,老BWBWBWBWBWBWBW
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-MBP/BF350 Conjugated antibody (bs-0380R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0380R-BF350
英文名稱1 Rabbit Anti-MBP/BF350 Conjugated antibody
中文名稱 BF350標記的髓鞘堿性蛋白/磷脂堿性蛋白抗體
別    名 Myelin Basic Protein; Myelin basic protien; GDB; Golli MBP; Hemopoietic MBP; HMBPR; HUGO; MBP; MGC99675; MLD; Myelin A1 Protein; Myelin Deficient; Myelin Membrane Encephalitogenic Protein; SHI; Shiverer; SP; MBP_HUMAN .  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經(jīng)生物學  生長因子和激素  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, Pig, Guinea Pig, G)
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Gpig MBP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non classic group of MBP isoforms (isoforms 1 to 3/Golli MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T cells and neural cells. Differential splicing events combined to optional posttranslational modifications give a wide spectrum of isomers, each of them having maybe a specialized function.

Function:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Subunit:
Homodimer. Isoform 3 exists as a homodimer.

Subcellular Location:
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.

Tissue Specificity:
MBP isoforms are found in both the central and the peripheral nervous system, whereas Golli-MBP isoforms are expressed in fetal thymus, spleen and spinal cord, as well as in cell lines derived from the immune system.

Post-translational modifications:
Several charge isomers of MBP; C1 (the most cationic, least modified, and most abundant form), C2, C3, C4, C5, C6, C7, C8-A and C8-B (the least cationic form); are produced as a result of optional PTM, such as phosphorylation, deamidation of glutamine or asparagine, arginine citrullination and methylation. C8-A and C8-B contain each two mass isoforms termed C8-A(H), C8-A(L), C8-B(H) and C8-B(L), (H) standing for higher and (L) for lower molecular weight. C3, C4 and C5 are phosphorylated. The ratio of methylated arginine residues decreases during aging, making the protein more cationic.
The N-terminal alanine is acetylated (isoform 3, isoform 4, isoform 5 and isoform 6).
Arg-241 was found to be 6% monomethylated and 60% symmetrically dimethylated.
Phosphorylated by TAOK2, VRK2, MAPK11, MAPK12, MAPK14 and MINK1.

Similarity:
Belongs to the myelin basic protein family.

Database links:

Gene ID: 100731253 Guinea pig

Entrez Gene: 4155 Human

Entrez Gene: 17196 Mouse

Entrez Gene: 414286 Pig

Entrez Gene: 24547 Rat

Omim: 159430 Human

SwissProt: P02686 Human

SwissProt: P04370 Mouse

SwissProt: P81558 Pig

SwissProt: P25274 Rabbit

SwissProt: P02688 Rat

Unigene: 551713 Human

Unigene: 63285 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

神經(jīng)生物學相關蛋白(Neurobiology)

少突膠質細胞標志物
主要用于脊髓脫髓鞘病-脊髓多發(fā)硬化癥的研究。
MBP髓鞘堿性蛋白和髓鞘相伴糖蛋白是多發(fā)性硬化的自身免疫攻擊的靶。
Myelin basic protein (MPB) :Oligodendrocyte Protein produced by mature oligodendrocytes; located in the myelin sheath surrounding neuronal structures 髓磷脂Myelin/oligodendrocyte specific protein (MOSP)是由中樞神經(jīng)系統(tǒng)中少突膠質細胞和外周神經(jīng)系統(tǒng)中雪旺氏細胞產(chǎn)生特殊蛋白質。是形成髓鞘的主要成分,對于引導神經(jīng)沖動的傳遞起著致關重要的作用。 多年來,關于髓鞘的形成機理和與其相關的一些先天性疾病的發(fā)病機制一直是眾多科學家關注的重點。如:多重硬化癥和腦白質營養(yǎng)不良等,都與神經(jīng)系統(tǒng)的去髓鞘化相關。
版權所有 2004-2026 www.xucheq.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
中文乱码人妻系列一区二区| 免费的视频APP网站| 无码人妻精品一区二区三区不卡| 丰满老熟好大BBB| 国产乱子伦精品无码专区| 69久久无码一区人妻A片| 丝袜老师办公室里做好紧好爽| 少妇高潮喷水久久久影院| 两女互摸自慰喷水爽哭直播了| 国产伦孑沙发午休精品| av无码久久久久久不卡网站| 亚洲欧美一区二区三区在线| 久久久精品国产SM调教网站| 亚洲AV无码国产综合专区| 国产成人精品A视频一区| 少妇特黄A一区二区三区| 男人J桶进女人P无遮挡全过程| AV无码免费一区二区三区| 亚洲AV无码乱码在线观看| 中文字幕乱妇无码AV在线| 午夜精品久久久久久久无码 | 少妇高潮惨叫久久久久电影69 | 国产又黄又爽又猛免费视频播放| 久久久亚洲精品无码| 国产精品高潮呻吟AV久久动漫| 乳妓H军妓调教HH文| 麻豆传媒视频| 国产精品一区二区在线观看| 国模小黎自慰GOGO人体| 高清家庭影院| 七旬老人为满足需求| 精品国产污污免费网站AⅤ| 精品无码三级在线观看视频| 日日麻批免费40分钟无码| 国产成人无码AV| 欧美性受XXXX白人性爽| 俄罗斯大荫蒂女人毛茸茸| 99精品久久毛片A片| 成人性爱视频在线观看 | 成全动漫视频在线观看免费高清| 人物动物交互狗AA|